新型冠状病毒肺炎合并自发性气胸的预后影响
The prognostic effect of concomitant COVID-19 with spontaneous pneumothorax.
作者信息
Akyil Mustafa, Bayram Serkan, Erdizci Pelin, Tokgoz Akyil Fatma, Ulusoy Ayse, Evman Serdar, Alpay Levent, Baysungur Volkan
机构信息
Department of Thoracic Surgery, University of Health Sciences, Süreyyapaşa Training and Research Hospital, Istanbul, Türkiye.
Department of Pulmonology, University of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Türkiye.
出版信息
Turk Gogus Kalp Damar Cerrahisi Derg. 2023 Jul 27;31(3):352-357. doi: 10.5606/tgkdc.dergisi.2023.23439. eCollection 2023 Jul.
BACKGROUND
The aim of this study was to investigate the prevalence of novel coronavirus disease 2019 (COVID-19) in patients hospitalized with primary spontaneous pneumothorax and to evaluate its possible effects on the clinical course, treatment, and the prognosis.
METHODS
Between April 2020 and January 2021, a total of 86 patients (78 males, 8 females; mean age: 27±5 years; range, 16 to 40 years) who had no underlying lung disease and were diagnosed with the first episode of spontaneous pneumothorax were retrospectively analyzed. At the same time of diagnosis, all patients were screened for COVID-19 via polymerase chain reaction test of nasopharyngeal swabs. According to the test results, the patients were divided into two groups as COVID-19(+) and COVID-19(-). The duration of air leak, hospital stay, recurrence rates and treatment modalities, and mortality rates of the two groups were compared.
RESULTS
Following a pneumothorax diagnosis, 18 (21%) patients were diagnosed with COVID-19. In COVID-19(+) patients, the mean air leak and lung expansion duration were significantly longer (p<0.0001 for both). In these patients, the mean length of hospital stay was also significantly longer (p<0.0001). During the median follow-up of six months, no mortality was observed and the recurrence rate was similar between the two groups (p=0.998).
CONCLUSION
Our study results suggest that COVID-19 negatively affects the recovery time in patients with spontaneous pneumothorax.
背景
本研究旨在调查因原发性自发性气胸住院患者中2019冠状病毒病（COVID-19）的患病率，并评估其对临床病程、治疗及预后的可能影响。
方法
回顾性分析2020年4月至2021年1月期间86例无基础肺部疾病且被诊断为首次自发性气胸的患者（78例男性，8例女性；平均年龄：27±5岁；范围16至40岁）。在诊断的同时，通过鼻咽拭子聚合酶链反应检测对所有患者进行COVID-19筛查。根据检测结果，将患者分为COVID-19阳性组和COVID-19阴性组。比较两组的漏气持续时间、住院时间、复发率及治疗方式和死亡率。
结果
气胸诊断后，18例（21%）患者被诊断为COVID-19。COVID-19阳性患者的平均漏气和肺复张持续时间显著更长（两者均p<0.0001）。这些患者的平均住院时间也显著更长（p<0.0001）。在六个月的中位随访期间，未观察到死亡情况，两组的复发率相似（p=0.998）。
结论
我们的研究结果表明，COVID-19对自发性气胸患者的恢复时间有负面影响。
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