Köse Selçuk
Bakırköy Dr. Sadi Konuk Research and Education Hospital, Thoracic Surgery Department, İstanbul, Turkey.
Turk Thorac J. 2022 Sep;23(5):343-347. doi: 10.5152/TurkThoracJ.2022.22061.
It is still unknown how to call the pneumothorax that develops during the recovery period after coronavirus disease 2019. Patients who developed pneumothorax during the recovery period after coronavirus disease 2019 were compared with those who had a primary or secondary spontaneous pneumothorax without a coronavirus disease 2019 history.
Between 2020 and 2021, 160 patients with pneumothorax were retrospectively analyzed. Twenty-three patients had a history of coronavirus disease 2019 (coronavirus disease recovery) confirmed by real-time reverse transcriptase-polyme rase chain reaction, whereas the remaining 137 patients did not have a history of coronavirus disease 2019 (18 of the patients with secondary spontaneous pneumothorax group and 119 patients with primary spontaneous pneumothorax group).
The median time between discharge and readmission to the hospital because of pneumothorax was 9 days in the coronavirus disease recovery group. There were statistically significant differences in regards to age (P < .001), gender (P = .02), the presence of bullae (P = .02), and dystrophic severity lung score (P = .04) between the coronavirus disease recovery and primary spontaneous pneumothorax groups, whereas no difference was found between the coronavirus disease recovery and the secondary spontaneous pneumothorax groups (P > .05). The prolonged air leak was observed in 17.6% (n = 25). Patients who had prolonged air leak were statistically higher in the coronavirus disease recovery group than the primary spontaneous pneumothorax group (56.5% vs. 10.1%), although it was almost similar between the coronavirus disease recovery and secondary spontaneous pneumothorax groups (P = .951). On logistic regression analysis, the coronavirus disease recovery group was the independent factor for prolonged air leak (odds ratio = 9.900, 95% CI = 1.557- 62.500, P = .01).
Pneumothorax may be developed during the recovery period after coronavirus disease 2019 in patients with previously healthy lungs, and it should be called as secondary spontaneous pneumothorax.
目前仍不清楚如何称呼2019冠状病毒病恢复期出现的气胸。将2019冠状病毒病恢复期出现气胸的患者与无2019冠状病毒病病史的原发性或继发性自发性气胸患者进行比较。
回顾性分析2020年至2021年间160例气胸患者。23例患者经实时逆转录聚合酶链反应确诊有2019冠状病毒病病史（冠状病毒病康复期），其余137例患者无2019冠状病毒病病史（继发性自发性气胸组18例，原发性自发性气胸组119例）。
冠状病毒病康复组因气胸出院至再次入院的中位时间为9天。冠状病毒病康复组与原发性自发性气胸组在年龄（P <.001）、性别（P =.02）、肺大疱的存在（P =.02）和营养不良严重程度肺评分（P =.04）方面存在统计学显著差异，而冠状病毒病康复组与继发性自发性气胸组之间未发现差异（P >.05）。观察到17.6%（n = 25）的患者存在持续漏气。冠状病毒病康复组持续漏气的患者在统计学上高于原发性自发性气胸组（56.5%对10.1%），尽管冠状病毒病康复组与继发性自发性气胸组之间几乎相似（P =.951）。经逻辑回归分析，冠状病毒病康复组是持续漏气的独立因素（比值比 = 9.900，95%可信区间 = 1.557 - 62.500，P =.01）。
既往肺部健康的患者在2019冠状病毒病恢复期可能发生气胸，应称为继发性自发性气胸。
