Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Department of Internal Medicine, Tampere University Hospital, Tampere, Finland.
Acta Ophthalmol. 2024 Jun;102(4):435-440. doi: 10.1111/aos.15749. Epub 2023 Sep 4.
Systematic ocular screening is recommended in sarcoidosis, because of a high rate of ocular involvement. The purpose of this study was to determine whether ocular screening is useful in sarcoidosis in a Finnish university hospital population with 0.5 M inhabitants.
Patient charts of patients with sarcoidosis, without a history of ocular sarcoidosis, without ocular inflammatory symptoms, and with a comprehensive eye exam from January 2014 to January 2021 at Tays Eye Centre, Tampere, Finland, were studied.
Five of 262 patients (2%) were diagnosed with asymptomatic uveitis. No other types of ocular sarcoidosis were found. Anterior uveitis without complications was present in three patients, unilaterally in two and bilaterally in one patient. Posterior uveitis was present in two patients, a unilateral choroidal granuloma requiring treatment in one and bilateral punched-out chorioretinal lesions in the other patient.
With this low rate of ocular involvement requiring treatment in sarcoidosis, systematic screening for asymptomatic ocular sarcoidosis does not seem useful in a Finnish population. In Tays Eye Centre, systematic screening of ocular sarcoidosis was discontinued in 2021.
由于眼部受累率高，建议对结节病进行系统性眼部筛查。本研究旨在确定在芬兰一所拥有 0.5 百万居民的大学附属医院人群中，眼部筛查对结节病是否有用。
研究了 2014 年 1 月至 2021 年 1 月期间在芬兰坦佩雷 Tays Eye 中心接受全面眼部检查、无眼部结节病病史、无眼部炎症症状且无眼部炎症症状的结节病患者的病历。
262 例患者中有 5 例（2%）被诊断为无症状葡萄膜炎。未发现其他类型的眼部结节病。3 例患者存在无前葡萄膜炎，2 例单侧，1 例双侧。2 例患者存在后葡萄膜炎，1 例单侧脉络膜肉芽肿需要治疗，另 1 例双侧孔状眼脉络膜视网膜病变。
鉴于这种需要治疗的眼部受累率低，对无症状眼部结节病进行系统筛查似乎在芬兰人群中并不有用。在 2021 年，Tays Eye 中心停止了对眼部结节病的系统筛查。
