Leinonen Sanna
Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Tays Eye Centre, Tampere University Hospital, Tampere, Finland.
Front Med (Lausanne). 2024 Feb 19;11:1348435. doi: 10.3389/fmed.2024.1348435. eCollection 2024.
Ocular sarcoidosis most commonly presents with symptoms and is first diagnosed before systemic sarcoidosis in at least half of the patients with sarcoidosis. Prevalence of ocular involvement in sarcoidosis varies between 2-80% depending on the study setting, included ocular diseases, and studied population. In many studies, ocular involvement in sarcoidosis has been overestimated mainly because study populations have been collected from eye clinics and because the study criteria have included ocular findings or symptoms that do not require treatment or monitoring. In a screening setting, asymptomatic ocular sarcoidosis has been detected in only 2-5%. 0-1% of the screened sarcoidosis patients have required treatment. For these reasons, ocular screening in sarcoidosis seems generally of little value. Patients with sarcoidosis who present with ocular symptoms should be screened for ocular sarcoidosis in a timely manner because they are at high risk of ocular disease.
眼部结节病最常出现症状，在至少一半的结节病患者中，眼部结节病在系统性结节病之前就被首次诊断出来。根据研究背景、纳入的眼部疾病以及研究人群的不同，结节病眼部受累的患病率在2%至80%之间波动。在许多研究中，结节病眼部受累情况被高估了，主要原因是研究人群是从眼科诊所收集的，且研究标准包括了不需要治疗或监测的眼部发现或症状。在筛查环境中，无症状性眼部结节病仅在2%至5%的人群中被检测到。0%至1%的接受筛查的结节病患者需要治疗。由于这些原因，结节病的眼部筛查总体上似乎价值不大。出现眼部症状的结节病患者应及时接受眼部结节病筛查，因为他们患眼部疾病的风险很高。
