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膜性肾小球肾炎和兰德里-古兰-巴雷综合征。

Membranous glomerulonephritis and Landry-Guillain-Barre syndrome.

作者信息

Murphy B F, Gonzales M F, Ebeling P, Fairley K F, Kincaid-Smith P

出版信息

Am J Kidney Dis. 1986 Oct;8(4):267-70. doi: 10.1016/s0272-6386(86)80039-7.

Abstract

Two cases of idiopathic membranous glomerulonephritis associated with acute inflammatory demyelinating polyradiculoneuropathy (Landry-Guillian-Barre syndrome) are described. In both of the patients, the onset of the nephrotic syndrome coincided with the development of severe ascending sensorimotor neuropathy. Although this association has previously been reported in four other isolated cases, it is not generally recognized by nephrologists and may be of significance in the future understanding of the immunopathogenesis of both diseases.

摘要

本文描述了两例特发性膜性肾小球肾炎合并急性炎症性脱髓鞘性多发性神经根神经病(兰德里-吉兰-巴雷综合征)的病例。两名患者的肾病综合征发作均与严重的上行性感觉运动神经病的发展同时出现。尽管此前在其他四例孤立病例中也曾报道过这种关联,但肾脏病学家尚未普遍认识到这一点,并且这可能对未来理解这两种疾病的免疫发病机制具有重要意义。

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