Fujiwara Kengo, Kato Takuma, Ibuki Emi, Kimura Nachino, Kaku Yo, Tsunemori Hiroyuki, Miura Takayoshi, Dainichi Teruki, Haba Reiji, Sugimoto Mikio
Department of Urology Kagawa University Faculty of Medicine Miki-cho Kagawa Japan.
Departments of Diagnostic Pathology, Faculty of Medicine Kagawa University Miki-cho Kagawa Japan.
IJU Case Rep. 2023 Jul 23;6(5):290-292. doi: 10.1002/iju5.12606. eCollection 2023 Sep.
Skin tissue contamination within transcutaneous visceral organ biopsies is seldom found. We encountered a rare case of extramammary Paget's disease incidentally diagnosed by prostate biopsy during active surveillance for prostate cancer.
A 71-year-old Japanese patient was diagnosed with prostate cancer, and active surveillance was selected. After 1 year, prostate biopsy was performed by a transperitoneal approach, and 16 biopsy cores were taken. One biopsy core contained skin tissue showing extramammary Paget's disease. Careful skin examination confirmed the presence of an extramammary Paget's disease lesion in the left perineum, and curative surgical resection was performed. Recurrence and metastasis did not occur after 6 months of follow-up.
Although the perianal region is a common site of extramammary Paget's disease, early-stage extramammary Paget's disease is often asymptomatic. Thus, during a transcutaneous biopsy, it is important to consider the appearance of the skin and the pathological features of migrating skin tissue.
经皮内脏器官活检中很少发现皮肤组织污染情况。我们遇到了一例罕见病例,在对前列腺癌进行主动监测期间,经前列腺活检偶然诊断出乳腺外佩吉特病。
一名71岁的日本患者被诊断为前列腺癌,并选择了主动监测。1年后,通过经腹途径进行前列腺活检,获取了16个活检组织芯。其中一个活检组织芯包含显示乳腺外佩吉特病的皮肤组织。仔细的皮肤检查证实左侧会阴存在乳腺外佩吉特病病变,并进行了根治性手术切除。随访6个月后未发生复发和转移。
虽然肛周区域是乳腺外佩吉特病的常见部位,但早期乳腺外佩吉特病通常无症状。因此,在经皮活检过程中,考虑皮肤外观和迁移皮肤组织的病理特征很重要。