Noda Taisho, Fujisaki Akira, Uchida Kosuke, Iijima Heisuke, Hakamata Yasuhiro, Kanda Yuka, Imai Shin, Otsuki Yoshiro, Yoneda Tatsuaki
Department of Urology Seirei Hamamatsu General Hospital Hamamatsu Japan.
Department of Pathology Seirei Hamamatsu General Hospital Hamamatsu Japan.
IJU Case Rep. 2023 Jun 27;6(5):274-277. doi: 10.1002/iju5.12602. eCollection 2023 Sep.
Prostatic metastasis from testicular cancer is extremely rare, with only 10 reported cases, all of which were diagnosed as relapse. Herein, we report the case of a patient with concurrent testicular cancer and prostatic metastasis.
A 57-year-old man presented at our emergency department with urinary retention. A painless mass was found in the right scrotum, and computed tomography showed lung, mediastinal, and liver metastases, and an enlarged prostate. Tumor markers were measured in 2057 U/L lactate dehydrogenase, 2460 mIU/mL human chorionic gonadotrophin, 1303 ng/mL alpha-fetoprotein, and 1.51 ng/mL prostate specific antigen. An orchiectomy and biopsy were performed; the pathological results showed immature teratomas, embryonal carcinomas, choriocarcinomas, and seminomas in the testis, and embryonal carcinomas in the prostate, liver, and mediastinum. The patient refused chemotherapy and died 3 months following diagnosis.
Prostatic metastasis should be considered in cases of dysuria or prostate enlargement in testicular cancers.
睾丸癌发生前列腺转移极为罕见，仅有10例报道，所有病例均被诊断为复发。在此，我们报告一例同时患有睾丸癌和前列腺转移的患者。
一名57岁男性因尿潴留就诊于我院急诊科。右侧阴囊发现无痛性肿块，计算机断层扫描显示肺部、纵隔和肝脏转移，以及前列腺肿大。检测肿瘤标志物，乳酸脱氢酶为2057 U/L，人绒毛膜促性腺激素为2460 mIU/mL，甲胎蛋白为1303 ng/mL，前列腺特异性抗原为1.51 ng/mL。进行了睾丸切除术和活检；病理结果显示睾丸中有未成熟畸胎瘤、胚胎癌、绒毛膜癌和精原细胞瘤，前列腺、肝脏和纵隔中有胚胎癌。患者拒绝化疗，诊断后3个月死亡。
睾丸癌患者出现排尿困难或前列腺肿大时应考虑前列腺转移。
