Zhou Yiwei, Huang Yu, Wu Chunhua, Yang Hongsheng, Shan Chunyan, Zhou Zumu
Business School, University of Shanghai for Science and Technology, Shanghai, People's Republic of China.
The Affiliated Kangning Hospital of Wenzhou Medical University Zhejiang Provincial Clinical Research Center for Mental Disorders, Wenzhou, People's Republic of China.
Infect Drug Resist. 2023 Aug 30;16:5719-5728. doi: 10.2147/IDR.S416565. eCollection 2023.
Coronavirus disease (COVID-19) mainly caused by the Omicron virus strain currently is still prevalent worldwide, and many medical institutions have experienced COVID-19 outbreaks in the past three years.
This article reported COVID-19 outbreak among health care workers in a mental hospital to clarify the epidemiological and clinical characteristics of COVID-19 outbreak in a medical institution, to assess the susceptible factors related to COVID-19 among these personnel and to evaluate the effect of COVID-19 vaccine on the medical workers.
A uniform questionnaire was used to investigate all employees, including age, gender, department, time of onset, clinical symptoms, vaccination status. At the same, the results of laboratory testing, chest computed tomography (CT) and/or X-ray examination were collected.
Among 1047 hospital employees, 842 cases were diagnosed as COVID-19, with a total attack rate of 80.42%. The attack rate of doctors, nurses, medical technicians, and administrators (83.50-90.67%) was higher than that of logistics departments (56.81%). Out of the 842 patients, 9 were hospitalized; 833 were non-hospitalized patients who belong to mild or moderate cases. No deaths were reported. The full vaccination rate and booster rate of COVID-19 vaccine were 78.26% and 80.87%, respectively. There was no significant correlation between the attack rate and COVID-19 vaccine ( = 3.41 > 0.05).
This is an outbreak of COVID-19 with a high attack rate among employees in a mental hospital. The attack rate of medical personnel is higher than that of logistics personnel, which may be related to opportunities and duration of contact with infected individuals. COVID-19 vaccine has no significant protective effect on patients with mild or moderate symptoms 13 months after the full vaccination. It is suggested that they should be timely boostered with COVID-19 vaccine to maintain their immunity to the disease.
目前主要由奥密克戎毒株引起的冠状病毒病（COVID-19）仍在全球流行，在过去三年中许多医疗机构都经历了COVID-19疫情暴发。
本文报告一家精神病医院医护人员中COVID-19疫情，以阐明医疗机构中COVID-19疫情的流行病学和临床特征，评估这些人员中与COVID-19相关的易感因素，并评估COVID-19疫苗对医护人员的效果。
使用统一问卷对所有员工进行调查，内容包括年龄、性别、科室、发病时间、临床症状、疫苗接种状况。同时，收集实验室检测结果、胸部计算机断层扫描（CT）和/或X线检查结果。
在1047名医院员工中，842例被诊断为COVID-19，总发病率为80.42%。医生、护士、医技人员和行政管理人员的发病率（83.50% - 90.67%）高于后勤部门（56.81%）。842例患者中，9例住院；833例为非住院患者，属于轻症或中症病例。无死亡报告。COVID-19疫苗全程接种率和加强免疫接种率分别为78.26%和80.87%。发病率与COVID-19疫苗之间无显著相关性（ = 3.41 > 0.05）。
这是一家精神病医院员工中COVID-19的一次高发病率疫情。医务人员的发病率高于后勤人员，这可能与接触感染个体的机会和时长有关。COVID-19疫苗在全程接种13个月后对轻症或中症患者无显著保护作用。建议及时对其进行COVID-19疫苗加强免疫以维持对该疾病的免疫力。
