Zhao Christopher H, Koneru Manisha, Siegler James E, Vigilante Nicholas, Khalife Jane, Tonetti Daniel A, Shaikh Hamza
Cooper Medical School of Rowan University, Camden, NJ, USA.
Cooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Interv Neuroradiol. 2023 Sep 6:15910199231199880. doi: 10.1177/15910199231199880.
Endovascular mechanical thrombectomy has been shown to benefit select patients with acute ischemic stroke caused by medium vessel occlusion, aided by recent advancements in endovascular mechanical thrombectomy devices that facilitate navigation through narrower vasculature. In this study, we aim to evaluate the safety and efficacy of using the 3 mm Trevo NXT stent retriever (Stryker, Kalamazoo, MI) for endovascular mechanical thrombectomy in patients with acute ischemic stroke caused by medium vessel occlusion.
From our single-center registry, we performed a retrospective review of all acute ischemic stroke patients from 2018 to 2022 who underwent endovascular mechanical thrombectomy for medium vessel occlusion with a 3 mm Trevo NXT. We examined efficacy outcomes (modified thrombolysis in cerebral infarction and puncture-to-revascularization time), clinical outcomes (National Institutes of Health Stroke Scale), and procedural complication rate.
Between 2018 and 2022, 44 patients (52.2% female, mean age 71.1 years, median National Institutes of Health Stroke Scale of 15 [8-22.8]) met our inclusion criteria. The 3 mm Trevo NXT was used in the first pass in 56.9% of individuals, with 72.4% achieving successful recanalization (modified thrombolysis in cerebral infarction ≥ 2B). The 3 mm Trevo NXT was used as "rescue" after initial revascularization failure in 43.1% of individuals, achieving successful recanalization in 60.0% of passes. Acute complications were reported in 2.4% of cases. Median National Institutes of Health Stroke Scale at 24 h after intervention was 12 (4-20.8).
Our results suggest that endovascular mechanical thrombectomy using the 3 mm Trevo NXT is a safe and effective treatment option for medium vessel occlusion. The utility of novel stent retrievers in the treatment of medium vessel occlusion should be further explored in future multicenter studies.
血管内机械取栓已被证明对某些由中等血管闭塞引起的急性缺血性卒中患者有益,这得益于血管内机械取栓设备的最新进展,这些进展有助于在更狭窄的血管系统中导航。在本研究中,我们旨在评估使用3毫米Trevo NXT支架取栓器(史赛克公司,密歇根州卡拉马祖)对由中等血管闭塞引起的急性缺血性卒中患者进行血管内机械取栓的安全性和有效性。
从我们的单中心登记处,我们对2018年至2022年期间所有因中等血管闭塞接受3毫米Trevo NXT血管内机械取栓的急性缺血性卒中患者进行了回顾性研究。我们检查了疗效结果(改良脑梗死溶栓和穿刺至再通时间)、临床结果(美国国立卫生研究院卒中量表)和手术并发症发生率。
在2018年至2022年期间,44例患者(52.2%为女性,平均年龄71.1岁,美国国立卫生研究院卒中量表中位数为15[8 - 22.8])符合我们的纳入标准。56.9%的个体首次使用3毫米Trevo NXT,其中72.4%实现成功再通(改良脑梗死溶栓≥2B)。43.1%的个体在初始再通失败后将3毫米Trevo NXT用作“补救”,其中60.0%的操作实现成功再通。2.4%的病例报告有急性并发症。干预后24小时美国国立卫生研究院卒中量表中位数为12(4 - 20.8)。
我们的结果表明,使用3毫米Trevo NXT进行血管内机械取栓是治疗中等血管闭塞的一种安全有效的治疗选择。新型支架取栓器在中等血管闭塞治疗中的效用应在未来的多中心研究中进一步探索。