University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
Boston University SchooI of Medicine, Boston, Massachusetts, USA.
Breastfeed Med. 2023 Sep;18(9):645-665. doi: 10.1089/bfm.2023.0118. Epub 2023 Sep 6.
Postpartum contraceptive use can help prevent short-interval pregnancies, which have been associated with adverse neonatal and maternal health outcomes. Many contraceptive methods are safe for postpartum use, but patients and providers may be confused as to what impact hormonal contraception has on lactation. We performed a scoping review of the most recent U.S.-based guidelines regarding hormonal contraception on lactation to provide synthesis and recommendations to aid providers in counseling their patients. We conducted a scoping review by identifying the most recent clinical recommendations and guidelines from the Centers for Disease Control and Prevention (CDC) and three maternal and child health professional associations (American College of Obstetricians and Gynecologists [ACOG], Society for Maternal-Fetal Medicine [SMFM], and Academy of Breastfeeding Medicine [ABM]). We also reviewed the citations in these guidelines used in their development. We then conducted an updated literature review to capture studies published since the most recent systematic reviews were conducted. We reviewed 1 clinical guideline from the CDC and 2 systematic reviews cited in its references, 6 professional association recommendations, and 28 publications identified through the updated literature review. Progestin-only contraceptive methods continue to demonstrate safety in breastfeeding patients, while low-quality evidence supports concerns of decreased milk supply with combined hormonal contraception. Organizations should consider updating counseling recommendations regarding progestin-only contraceptives and lactation. Further research is needed to examine new contraceptive methods as well as the effect of hormonal contraception on lactation in the setting of preterm birth.
产后避孕措施有助于预防间隔时间较短的妊娠,因为这类妊娠与新生儿和产妇健康不良结局相关。许多避孕方法在产后使用是安全的,但患者和提供者可能会对激素避孕对哺乳的影响感到困惑。我们对美国最近基于激素避孕的产后使用的指南进行了范围界定审查,以提供综合建议,帮助提供者为患者提供咨询。
我们通过确定美国疾病控制与预防中心 (CDC) 和三个母婴健康专业协会 (美国妇产科医师学会 [ACOG]、母胎医学学会 [SMFM] 和哺乳医学学会 [ABM]) 的最新临床建议和指南来进行范围界定审查。我们还审查了这些指南中用于制定指南的参考文献。然后,我们进行了更新的文献综述,以捕获自最近进行的系统评价以来发表的研究。
我们审查了来自 CDC 的 1 份临床指南和其参考文献中引用的 2 项系统评价、6 项专业协会建议和通过更新的文献综述确定的 28 项出版物。仅孕激素避孕方法继续在哺乳患者中表现出安全性,而低质量证据支持对联合激素避孕方法减少乳汁供应的担忧。
各组织应考虑更新关于仅孕激素避孕药和哺乳的咨询建议。需要进一步研究新的避孕方法以及在早产背景下激素避孕对哺乳的影响。