Schlegel Patrick, Chung Hye Rhyn, Döllinger Michael, Chhetri Dinesh K
Department of Head and Neck Surgery, University of California, Los Angeles, Los Angeles, California, U.S.A.
Division of Phoniatrics and Pediatric Audiology, Department of Head and Neck Surgery, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.
Laryngoscope. 2024 Mar;134(3):1249-1257. doi: 10.1002/lary.31029. Epub 2023 Sep 6.
Analysis of medial surface dynamics of the vocal folds (VF) is critical to understanding voice production and treatment of voice disorders. We analyzed VF medial surface vibratory dynamics, evaluating the effects of airflow and nerve stimulation using 3D reconstruction and empirical eigenfunctions (EEF).
In vivo canine hemilarynx phonation.
An in vivo canine hemilarynx was phonated while graded stimulation of the recurrent and superior laryngeal nerves (RLN and SLN) was performed. For each phonatory condition, vibratory cycles were 3D reconstructed from tattooed landmarks on the VF medial surface at low, medium, and high airflows. Parameters describing medial surface trajectory shape were calculated, and underlying patterns were emphasized using EEFs. Fundamental frequency and smoothed cepstral peak prominence (CPPS) were calculated from acoustic data.
Convex-hull area of landmark trajectories increased with increasing flow and decreasing nerve activation level. Trajectory shapes observed included circular, ellipsoid, bent, and figure-eight. They were more circular on the superior and anterior VF, and more elliptical and line-like on the inferior and posterior VF. The EEFs capturing synchronal opening and closing (EEF1) and alternating convergent/divergent (EEF2) glottis shapes were mostly unaffected by flow and nerve stimulation levels. CPPS increased with higher airflow except for low RLN activation and very dominant SLN stimulation.
We analyzed VF vibration as a function of neuromuscular stimulation and airflow levels. Oscillation patterns such as figure-eight and bent trajectories were linked to high nerve activation and flow. Further studies investigating longer sections of 3D reconstructed oscillations are needed.
N/A, Basic Science Laryngoscope, 134:1249-1257, 2024.
分析声带（VF）内表面动力学对于理解发声和嗓音障碍的治疗至关重要。我们使用三维重建和经验特征函数（EEF）分析了VF内表面振动动力学，评估气流和神经刺激的影响。
犬半喉体内发声。
在对喉返神经和喉上神经（RLN和SLN）进行分级刺激的同时，使犬半喉在体内发声。对于每种发声条件，在低、中、高气流下从VF内表面的纹身标记点对振动周期进行三维重建。计算描述内表面轨迹形状的参数，并使用EEF突出潜在模式。从声学数据中计算基频和平滑的谐波峰值突出度（CPPS）。
标记点轨迹的凸包面积随着气流增加和神经激活水平降低而增加。观察到的轨迹形状包括圆形、椭圆形、弯曲形和8字形。它们在VF的上部和前部更呈圆形，在下部和后部更呈椭圆形和线状。捕获同步开闭（EEF1）和交替收敛/发散（EEF2）声门形状的EEF大多不受气流和神经刺激水平的影响。除了低RLN激活和非常占主导的SLN刺激外，CPPS随着气流增加而增加。
我们分析了VF振动与神经肌肉刺激和气流水平的关系。8字形和弯曲轨迹等振荡模式与高神经激活和气流有关。需要进一步研究三维重建振荡的更长节段。
无，基础科学《喉镜》，2024年，第134卷，第1249 - 1257页
