Bukharovich A M, Kuz'menko V A
Antibiot Med Biotekhnol. 1986 Jul;31(7):553-5.
The remote results of combined therapy of 300 patients with chronic pyoderma were estimated by the data of the 5-year catamneses. The patients were treated with the use of erycycline, a combined drug consisting of two antibiotics made in the USSR. Stable clinical recovery within 5 years was stated in 78.8 per cent of the patients. Significant improvement (single pustules 2-3 years after discontinuation of the treatment) was registered in 13.7 per cent of the patients. Improvement (insignificant relapses within the first 2 years) was stated in 6.3 per cent of the patients. No effect of the combined therapy was stated in 1.2 per cent of the patients. It was shown that the use of erycycline in the combined therapy of the patients with chronic pyoderma provided its high efficacy, favourable immediate and remote results, decreasing the treatment period at the average by 3.8 days and decreasing the number of relapses. It also provided economy. The analysis of the catamneses promoted critical and objective estimation of the treatment results and stability of the therapeutic remission thus facilitating solution of the problem of treatment and prophylaxis of chronic pyoderma.
根据5年随访数据评估了300例慢性脓皮病患者联合治疗的远期疗效。患者使用了erycycline进行治疗，erycycline是一种由苏联生产的两种抗生素组成的复方药物。78.8%的患者在5年内实现了临床稳定康复。13.7%的患者有显著改善（停药后2 - 3年出现单个脓疱）。6.3%的患者有改善（在最初2年内有轻微复发）。1.2%的患者联合治疗无效。结果表明，erycycline用于慢性脓皮病患者的联合治疗具有高效性，近期和远期疗效良好，平均治疗时间缩短3.8天，复发次数减少，还具有经济性。随访分析有助于对治疗结果进行批判性和客观评估，以及评估治疗缓解的稳定性，从而有助于解决慢性脓皮病的治疗和预防问题。
