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[来自左旋链霉菌K-3053的聚(甘油磷酸)性质的磷壁酸的结构及其生物学特性]

[Structure of teichoic acid of a poly(glycerophosphate) nature from Streptomyces levoris K-3053 and its biological properties].

作者信息

Vylegzhanina E S, Dmitrieva N F, Polin A N, Naumova I B, Epishin Iu N

出版信息

Antibiot Med Biotekhnol. 1986 Aug;31(8):584-7.

PMID:3767334
Abstract

The wall teichoic acid from S. levoris was studied. It is a poly(glycerophosphate)polymer consisting of 15-20 nonsubstituted glycerophosphate units coupled by the phosphodiether bonds according to the 1, 3 type. It was shown that the acid had antitumor activity and high cardiotoxicity evident from a clear-cut negative ionotropic effect on the cardiac papillar muscle in dogs.

摘要

对左旋糖多孢菌的壁磷壁酸进行了研究。它是一种聚(甘油磷酸)聚合物,由15 - 20个未取代的甘油磷酸单元组成,这些单元通过1,3型磷酸二醚键连接。结果表明,该酸具有抗肿瘤活性和高心脏毒性,从对犬心脏乳头肌明显的负性变力作用可明显看出。

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