From the Georgetown Multiple Sclerosis and Neuroimmunology Center (A.L.S., B.O., R.K.S.), Department of Neurology, MedStar Georgetown University Hospital, Washington, DC; Brigham Multiple Sclerosis Center (T.C.), Department of Neurology, Brigham and Women's Hospital, Boston, MA; Department of Neurosciences (J.S.G.), University of California San Diego School of Medicine, La Jolla; Department of Neurology (S.D.N.), Johns Hopkins University School of Medicine, Baltimore, MD; Department of Neurology and Program in Immunology (S.S.Z.), University of California, San Francisco; and Department of Pathology (I.H.S.), Brigham and Women's Hospital, Boston, MA.
Neurol Neuroimmunol Neuroinflamm. 2023 Sep 6;10(6). doi: 10.1212/NXI.0000000000200157. Print 2023 Nov.
A 28-year-old woman presented with subacute relapsing left-sided weakness. MRI demonstrated both enhancing C3-C6 and nonenhancing T2-T4 lesions. Initial provisional diagnosis was inflammatory/autoimmune. Her left-sided weakness progressed despite immunosuppressive therapies. We reassessed our original suspected diagnosis because of an atypical clinicoradiologic course, leading to biopsy and a definitive diagnosis.
一位 28 岁女性出现亚急性复发性左侧无力。MRI 显示 C3-C6 增强和 T2-T4 非增强病变。最初的暂定诊断为炎症/自身免疫。尽管进行了免疫抑制治疗，但她的左侧无力仍在进展。由于临床表现和影像学检查结果不典型，我们重新评估了最初的可疑诊断，进行了活检并做出了明确诊断。
