Otsuka F, Seki Y, Takizawa K, Ohara K, Ishibashi Y
Arch Dermatol. 1986 Oct;122(10):1176-9.
A 23-year-old woman presented with Trichosporon cutaneum, which invaded deep into the dermis and subcutaneous tissue of the face and developed chronic granulomatous reactions. We postulated that the local use of an occlusive dressing with topical corticosteroid ointment in the early stage of the infection played a role in promoting the process of this opportunistic fungal infection. Antifungal chemotherapies, selected according to sensitivity testing to the isolated organism, were unsuccessful, mainly because of the acquired resistance of the organism to the chemical agent. Surgery was finally performed and a good result was obtained.
一名23岁女性患皮肤毛孢子菌病，病菌侵入面部真皮和皮下组织并引发慢性肉芽肿反应。我们推测，感染早期局部使用封闭敷料和外用糖皮质激素软膏在这种机会性真菌感染的进展过程中起了促进作用。根据对分离出的病菌进行的药敏试验选择的抗真菌化疗未成功，主要原因是病菌对化学制剂产生了获得性耐药。最终实施了手术并取得了良好效果。
