Department of Prosthodontics, Rama Dental College Hospital and Research Centre, Kanpur, Uttar Pradesh, India.
Department of Prosthodontics, Gitam Dental College, Visakhapatnam, Andhra Pradesh, India.
Evid Based Dent. 2023 Dec;24(4):193. doi: 10.1038/s41432-023-00928-x. Epub 2023 Sep 6.
To evaluate the performance of complete-arch implant-supported fixed dental prostheses (FDPs) fabricated with polyetheretherketone (PEEK) and polyetherketoneketone (PEKK) framework in clinical cases.
This systematic review followed the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses and was registered in the International Prospective Register of Systematic Reviews with the number CRD42023399494. The electronic database PubMed, Cochrane Library and EBSCOhost were assessed for clinical research and reports on complete-arch implant-supported FDPs fabricated with PEEK and PEKK framework. Human studies with a minimum follow-up of 1 year and published in an English language were the only ones included.
The initial database and hand search provided 564 articles. Finally, 12 articles published between 2018 and 2022 were included in this systematic review. The mean follow-up ranged from 1 year to 6 years. The included studies reported 119 (114 PEEK, 5 PEKK) complete-arch implant-supported FDPs during 1 year follow-up. The cumulative survival rate of prostheses with PEEK as a framework was 97.3%. Prostheses fractures and complications were found with both PEEK and PEKK frameworks. No implant failure reported with both PEEK and PEKK prostheses.
In short-term follow-up, the complete-arch implant-supported FDPs with PEEK as a framework showed a good survival rate and acceptable health of the supporting tissues. The PEEK framework had shown adhesion issues as the most common prosthetic complication. Limited data were available on PEKK as framework material, so further long-term clinical trials are required.
评估采用聚醚醚酮（PEEK）和聚醚酮酮（PEKK）框架制作的全口种植体支持固定义齿（FDP）的临床性能。
本系统评价遵循系统评价和荟萃分析的首选报告项目（PRISMA）指南，并在国际前瞻性系统评价注册中心（CRD42023399494）进行了注册。评估了PubMed、Cochrane Library 和 EBSCOhost 电子数据库中的临床研究和关于采用 PEEK 和 PEKK 框架制作的全口种植体支持 FDP 的报告。仅纳入随访时间至少 1 年且以英文发表的人类研究。
最初的数据库和手工搜索共提供了 564 篇文章。最终，纳入了 2018 年至 2022 年期间发表的 12 篇文章进行系统评价。平均随访时间为 1 年至 6 年。纳入的研究报告了 119 例（114 例 PEEK，5 例 PEKK）全口种植体支持 FDP 在 1 年随访期间的情况。采用 PEEK 作为框架的修复体累积存活率为 97.3%。在 PEEK 和 PEKK 两种框架中均发现了修复体断裂和并发症。在 PEEK 和 PEKK 修复体中均未报告种植体失败。
在短期随访中，采用 PEEK 作为框架制作的全口种植体支持 FDP 显示出良好的存活率和可接受的支持组织健康状况。PEEK 框架最常见的修复体并发症是粘连问题。关于作为框架材料的 PEKK，可用数据有限，因此需要进一步进行长期临床试验。
