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2023年炎症性肠病对加拿大的影响:卫生系统直接成本和药物成本

The 2023 Impact of Inflammatory Bowel Disease in Canada: Direct Health System and Medication Costs.

作者信息

Kuenzig M Ellen, Coward Stephanie, Targownik Laura E, Murthy Sanjay K, Benchimol Eric I, Windsor Joseph W, Bernstein Charles N, Bitton Alain, Jones Jennifer L, Lee Kate, Peña-Sánchez Juan-Nicolás, Rohatinsky Noelle, Ghandeharian Sara, Im James H B, Jogendran Rohit, Meka Saketh, Weinstein Jake, Jones May Tyrel, Jogendran Manisha, Tabatabavakili Sahar, Hazan Elias, Hu Malini, Osei Jessica Amankwah, Khan Rabia, Wang Grace, Browne Mira, Davis Tal, Goddard Quinn, Gorospe Julia, Latos Kate, Mason Kate, Kerr Jack, Balche Naji, Sklar Anna, Kaplan Gilaad G

机构信息

SickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.

Child Health Evaluative Sciences, SickKids Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.

出版信息

J Can Assoc Gastroenterol. 2023 Sep 5;6(Suppl 2):S23-S34. doi: 10.1093/jcag/gwad008. eCollection 2023 Sep.

DOI:10.1093/jcag/gwad008
PMID:37674493
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10478805/
Abstract

Healthcare utilization among people living with inflammatory bowel disease (IBD) in Canada has shifted from inpatient management to outpatient management; fewer people with IBD are admitted to hospitals or undergo surgery, but outpatient visits have become more frequent. Although the frequency of emergency department (ED) visits among adults and seniors with IBD decreased, the frequency of ED visits among children with IBD increased. Additionally, there is variation in the utilization of IBD health services within and between provinces and across ethnocultural and sociodemographic groups. For example, First Nations individuals with IBD are more likely to be hospitalized than the general IBD population. South Asian children with Crohn's disease are hospitalized more often than their Caucasian peers at diagnosis, but not during follow-up. Immigrants to Canada who develop IBD have higher health services utilization, but a lower risk of surgery compared to individuals born in Canada. The total direct healthcare costs of IBD, including the cost of hospitalizations, ED visits, outpatient visits, endoscopy, cross-sectional imaging, and medications are rising rapidly. The direct health system and medication costs of IBD in Canada are estimated to be $3.33 billion in 2023, potentially ranging from $2.19 billion to $4.47 billion. This is an increase from an estimated $1.28 billion in 2018, likely due to sharp increases in the use of biologic therapy over the past two decades. In 2017, 50% of total direct healthcare costs can be attributed to biologic therapies; the proportion of total direct healthcare costs attributed to biologic therapies today is likely even greater.

摘要

加拿大炎症性肠病(IBD)患者的医疗保健利用模式已从住院治疗转向门诊治疗;IBD患者住院或接受手术的人数减少,但门诊就诊更为频繁。尽管成年和老年IBD患者到急诊科(ED)就诊的频率有所下降,但儿童IBD患者到ED就诊的频率却有所增加。此外,IBD医疗服务在省内、省际以及不同种族文化和社会人口群体之间的利用情况存在差异。例如,患有IBD的原住民比IBD总体人群更有可能住院。患有克罗恩病的南亚儿童在确诊时比白人同龄人住院更频繁,但在随访期间并非如此。与在加拿大出生的人相比,患IBD的加拿大移民医疗服务利用率更高,但手术风险更低。IBD的直接医疗总费用,包括住院、ED就诊、门诊就诊、内窥镜检查、横断面成像和药物费用,正在迅速上升。2023年,加拿大IBD的直接医疗系统和药物费用估计为33.3亿加元,可能在21.9亿加元至44.7亿加元之间。这比2018年估计的12.8亿加元有所增加,这可能是由于过去二十年生物疗法使用量的急剧增加。2017年,直接医疗总费用的50%可归因于生物疗法;如今,生物疗法在直接医疗总费用中所占比例可能更大。

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