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Response to paper by Binkowska . Risk of venous thromboembolism during the use of oral estrogen-progestogen hormone therapies in light of most recent research findings. Commentary: Oestradiol is not the holy grail in the quest for the ideal oestrogen therapy.

作者信息

Douxfils Jonathan, Foidart Jean-Michel, Gaspard Ulysse, Chatel Guillaume, Taziaux Mélanie, Jost Maud, Gérard Céline, Morimont Laure

机构信息

Department of Pharmacy, Namur Research for Life Sciences, Namur Thrombosis and Hemostasis Center, University of Namur, Namur, Belgium.

Department of Gynecology, University of Liège, Liège, Belgium.

出版信息

Prz Menopauzalny. 2023 Jun;22(2):117-119. doi: 10.5114/pm.2023.128815. Epub 2023 Jun 2.

DOI:10.5114/pm.2023.128815
PMID:37674929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10477764/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a52/10477764/3cdf9dc79598/MR-22-50886-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a52/10477764/3cdf9dc79598/MR-22-50886-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a52/10477764/3cdf9dc79598/MR-22-50886-g001.jpg

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本文引用的文献

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Impact of estetrol (E4) on hemostasis, metabolism and bone turnover in postmenopausal women.雌三醇（E4）对绝经后女性止血、代谢及骨转换的影响
Climacteric. 2023 Feb;26(1):55-63. doi: 10.1080/13697137.2022.2139599. Epub 2022 Nov 18.
2
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Prz Menopauzalny. 2022 Sep;21(3):197-199. doi: 10.5114/pm.2022.119861. Epub 2022 Oct 1.
3
Estetrol is not a SERM but a NEST and has a specific safety profile on coagulation.
雌三醇不是一种选择性雌激素受体调节剂（SERM），而是一种天然雌激素选择性靶点（NEST），并且在凝血方面具有特定的安全性。
Thromb Res. 2023 Dec;232:148-150. doi: 10.1016/j.thromres.2022.09.007. Epub 2022 Sep 16.
4
Low Thrombin Generation in Users of a Contraceptive Containing Estetrol and Drospirenone.使用含有屈螺酮和雌三醇的避孕药的女性，其凝血酶原生成减少。
J Clin Endocrinol Metab. 2022 Dec 17;108(1):135-143. doi: 10.1210/clinem/dgac511.
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A novel estetrol-containing combined oral contraceptive: European expert panel review.一种新型含依特醇的复方口服避孕药：欧洲专家小组评价。
Eur J Contracept Reprod Health Care. 2022 Oct;27(5):373-383. doi: 10.1080/13625187.2022.2093850. Epub 2022 Jul 21.
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Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause.雌三醇简介，一种有前景的口服避孕药天然雌激素和缓解更年期绝经期症状。
Expert Rev Clin Pharmacol. 2022 Feb;15(2):121-137. doi: 10.1080/17512433.2022.2054413. Epub 2022 Mar 27.
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Confirmation of the safety of combined oral contraceptives containing oestradiol on the risk of venous thromboembolism.含雌二醇复方口服避孕药对静脉血栓栓塞风险安全性的确认。
Eur J Contracept Reprod Health Care. 2022 Apr;27(2):83-84. doi: 10.1080/13625187.2022.2029397. Epub 2022 Feb 8.
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