Fiore A C, Ivey T D, McKeown P P, Misbach G A, Allen M D, Dillard D H
Ann Thorac Surg. 1986 Oct;42(4):372-9. doi: 10.1016/s0003-4975(10)60539-5.
Twenty-three patients with bacterial endocarditis and mycotic aneurysms of the aortic annulus were treated between 1978 and 1985. There were 18 men and 5 women ranging from 24 to 72 years old. All patients had congestive heart failure and positive blood cultures as a complication of the endocarditis and were in New York Heart Association (NYHA) Functional Class III or IV. The aneurysm complicated late prosthetic valve endocarditis in 7 patients and native valve endocarditis in 16. The most common infecting organisms were streptococci (12 patients) and staphylococci (7 patients). The noncoronary sinus was the most frequent site for aneurysm formation. Following debridement of the abscess cavity, the orifice of the aneurysm was closed with a patch of Dacron in 20 patients and autologous pericardium in 3. A prosthetic valve (18 bioprosthetic and 5 mechanical) was secured to the noninfected portion of the native annulus and to the patch at the level of annulus. There were 3 deaths, 1 perioperative and 2 late, each without evidence of residual infection or aortic insufficiency. There are 20 late survivors (87%). After a mean follow-up of 1 year, all patients are in NYHA Functional Class I. Patch closure of mycotic aneurysms involving the aortic annulus permits aggressive debridement of the abscess cavity and affords closure of the orifice without tension. The prosthetic valve can be seated at the level of the native annulus, thus avoiding complicated reconstructive procedures of the aortic root and coronary arteries. This technique is an effective alternative in selected cases of mycotic aneurysms involving the aortic annulus.
1978年至1985年间,对23例患有细菌性心内膜炎和主动脉瓣环霉菌性动脉瘤的患者进行了治疗。其中男性18例,女性5例,年龄在24岁至72岁之间。所有患者均患有充血性心力衰竭,血培养呈阳性,这是心内膜炎的并发症,且均处于纽约心脏协会(NYHA)心功能Ⅲ级或Ⅳ级。7例患者的动脉瘤并发于晚期人工瓣膜心内膜炎,16例并发于自体瓣膜心内膜炎。最常见的感染病原体是链球菌(12例患者)和葡萄球菌(7例患者)。非冠状动脉窦是动脉瘤形成最常见的部位。在清除脓肿腔后,20例患者用涤纶补片封闭动脉瘤开口,3例患者用自体心包封闭。将人工瓣膜(18个生物瓣和5个机械瓣)固定在自体瓣环的未感染部分以及瓣环水平的补片上。有3例死亡,1例围手术期死亡,2例晚期死亡,均无残余感染或主动脉瓣关闭不全的证据。有20例晚期存活者(87%)。平均随访1年后,所有患者的心功能均为NYHAⅠ级。对累及主动脉瓣环的霉菌性动脉瘤进行补片封闭,可积极清除脓肿腔,并能无张力地封闭开口。人工瓣膜可安置在自体瓣环水平,从而避免主动脉根部和冠状动脉复杂的重建手术。在某些累及主动脉瓣环的霉菌性动脉瘤病例中,该技术是一种有效的替代方法。