Lakshmanan M C, Hershey C O, Breslau D
Arch Intern Med. 1986 Oct;146(10):1931-4.
Complications of medical therapy requiring hospitalization affect the costs and quality of medical care. We studied all admissions to the medical services of a public teaching hospital to characterize current incidence and cause of iatrogenic admissions. We studied 834 admissions resulting in 47 distinct iatrogenic events and 45 iatrogenic admissions (5.4%). Thirty-five cases were caused by medications, nine by procedures, one by radiotherapy, one by transfusional therapy, and one by nosocomial infection. Almost 50% of these admissions were avoidable. Though the incidence of iatrogenic admissions in this study is similar to that in previous reports, the profile of the responsible agents is different. We did not find relationships with age, number or type of diagnoses, or number of medications on admission. Study of other patient and physician characteristics may be more rewarding in reducing the number of iatrogenic complications.
需要住院治疗的药物治疗并发症会影响医疗成本和质量。我们研究了一家公立教学医院医疗服务部门的所有住院病例，以确定当前医源性住院的发生率和原因。我们研究了834例住院病例，这些病例导致了47起不同的医源性事件和45例医源性住院（5.4%）。35例由药物引起，9例由手术引起，1例由放射治疗引起，1例由输血治疗引起，1例由医院感染引起。这些住院病例中近50%是可以避免的。虽然本研究中医源性住院的发生率与之前的报告相似，但责任因素的情况有所不同。我们没有发现与年龄、诊断数量或类型、入院时用药数量之间的关系。研究其他患者和医生特征可能在减少医源性并发症数量方面更有成效。
