Hao Zipeng, Zhanghuang Chenghao, Zhang Kun, Hang Yu, Ji Fengming, Yan Bing, Tang Haoyu
Department of Urology, Kunming Children's Hospital (Children's Hospital Affiliated to Kunming Medical University), Kunming, China.
Yunnan Province Clinical Research Center for Children's Health and Disease, Kunming Children's Hospital (Children's Hospital Affiliated to Kunming Medical University), Kunming, China.
Front Pediatr. 2023 Aug 22;11:1195900. doi: 10.3389/fped.2023.1195900. eCollection 2023.
Hamartoma is a mass formed by the proliferation and disorder of two or more kinds of cells inherent in normal organs or anatomical parts, which can occur in any part of the body. The most common hamartoma are kidney hamartoma, spleen hamartoma, liver hamartoma, and lung hamartoma. Urethral hamartoma is extremely rare in clinical practice.
Combined with literature review, the diagnosis and treatment process of a child with posterior urethral hamartoma and hypospadias in our hospital were analyzed. The patient was cured after surgical treatment, the lesion was completely removed, the appearance was satisfactory, and there was no recurrence, urethral stricture, urethral fistula, and other complications. The pathological results of this case support the histological diagnosis of hamartoma, which provides reference for the clinical diagnosis and treatment of congenital malformation and tumor of urogenital in children.
When a child has posterior urethral hamartoma, the symptoms may not be very typical, and it is often combined with urethral malformation. Therefore, it is necessary to perform careful physical examination combined with pathological examination to be able to make an accurate diagnosis. Under normal circumstances, the prognosis of urethral hamartoma is good. However, more cases are needed to be observed for verification, and a long-term effective follow-up after surgery is needed.
错构瘤是由正常器官或解剖部位固有的两种或两种以上细胞增生和紊乱形成的肿块,可发生于身体的任何部位。最常见的错构瘤有肾错构瘤、脾错构瘤、肝错构瘤和肺错构瘤。尿道错构瘤在临床实践中极为罕见。
结合文献复习,分析我院1例后尿道错构瘤合并尿道下裂患儿的诊治过程。患者经手术治疗后治愈,病变完全切除,外观满意,无复发、尿道狭窄、尿道瘘等并发症。本例病理结果支持错构瘤的组织学诊断,为儿童泌尿生殖系统先天性畸形及肿瘤的临床诊治提供参考。
儿童后尿道错构瘤时,症状可能不太典型,且常合并尿道畸形。因此,需要结合病理检查进行仔细的体格检查才能准确诊断。一般情况下,尿道错构瘤预后良好。然而,需要观察更多病例进行验证,术后需要进行长期有效的随访。