Department of Urology, Epsom and St Helier University Hospitals NHS Trust, London, United Kingdom.
Department of Surgery, College of Medicine, University of Lagos, Lagos, Nigeria.
Niger Postgrad Med J. 2023 Jul-Sep;30(3):218-225. doi: 10.4103/npmj.npmj_39_23.
Varicocele is a treatable aetiology of male infertility. Magnification with surgical loupe has been associated with improved outcome and reduced morbidity than the conventional technique without magnification.
To compare the outcomes of two techniques of subinguinal varicocelectomy, with a surgical loupe and without.
This was a prospective randomised hospital-based study. Forty-six patients were randomised to two arms - Group A: loupe-assisted subinguinal varicocelectomy (LASV) and Group B: open subinguinal varicocelectomy without Loupe (OSV). They all had their semen and hormonal parameters compared preoperatively and at 3 and 6 months postoperatively. Post-operative complications were also assessed. P < 0.05 was considered statistically significant.
The mean age was 38.28 ± 4.55 years with a range of 27-46 years. The mean age in Group A was 37.35 ± 4.68 and 39.22 ± 4.33 years in Group B. There was an improvement in motility, sperm count and concentration in both the groups at 3 and 6 months (P < 0.05). However, there was no difference in these parameters on comparison of the two groups at 3 and 6 months (P > 0.05). Follicle-stimulating hormone decline was significant in the OSV group at 3 and 6 months, P = 0.010 and 0.021, respectively. There was no difference in other hormonal parameters both at 3 and 6 months (P > 0.05). The pregnancy rate in each arm of study was 4.3%. All complications occurred in Group B.
Both techniques resulted in improvement in seminal fluid parameters. All complications occurred in the arm that had subinguinal varicocelectomy without loupe. Loupe-assisted subinguinal varicocelectomy is safe and effective.
精索静脉曲张是男性不育症的一种可治疗病因。与无放大的传统技术相比,使用手术放大镜放大可改善结果并降低发病率。
比较使用手术放大镜和不使用放大镜的两种精索内静脉结扎术的结果。
这是一项前瞻性随机医院基础研究。46 名患者随机分为两组:A 组:带手术放大镜的精索内静脉结扎术(LASV)和 B 组:无放大镜的开放精索内静脉结扎术(OSV)。所有患者均在术前和术后 3 个月和 6 个月比较精液和激素参数。还评估了术后并发症。P<0.05 被认为具有统计学意义。
平均年龄为 38.28±4.55 岁,范围为 27-46 岁。A 组的平均年龄为 37.35±4.68 岁,B 组为 39.22±4.33 岁。两组在术后 3 个月和 6 个月时的活力、精子计数和浓度均有所改善(P<0.05)。然而,两组在 3 个月和 6 个月时这些参数的比较没有差异(P>0.05)。OSV 组在术后 3 个月和 6 个月时卵泡刺激素下降显著,P=0.010 和 0.021。其他激素参数在 3 个月和 6 个月时均无差异(P>0.05)。每个研究组的妊娠率均为 4.3%。所有并发症均发生在 B 组。
两种技术均导致精液参数改善。所有并发症均发生在未使用放大镜的精索内静脉结扎术组。带手术放大镜的精索内静脉结扎术安全有效。