Department of Otorhinolaryngology-Head and Neck Surgery, Chongqing General Hospital; Department of Otorhinolaryngology, Chongqing Medical University, Chongqing, China.
Department of Otorhinolaryngology. Head and Neck Surgery, Chongqing General Hospital, Chongqing, China.
J Cancer Res Ther. 2023 Aug;19(4):1070-1073. doi: 10.4103/jcrt.jcrt_2096_22.
An 8-year-old child was admitted to our ENT department for a year because of a hoarse voice. An endoscopic examination displayed that a cystic, solid lesion can be seen in the right subglottis. The lesion was removed using a CO2 laser under general anesthesia. Postoperative histopathology confirmed granular cell tumor (GCT), S-100(+), vimentin (+), and SOX-10(+). GCT, also known as the Abrikossoff tumor, is a rare benign tumor that rarely occurs in the larynx, particularly in children. This case report emphasizes that considerable attention should be given to the differential diagnosis of the laryngeal granulosa cell tumor. Given the recurrence risk of GCT, long-term postoperative follow-up is necessary.
一位 8 岁儿童因声音嘶哑在我院耳鼻喉科就诊 1 年余。电子喉镜检查发现右侧声门下区可见囊性、实性占位。在全麻下行 CO2 激光切除，术后病理提示颗粒细胞瘤（GCT），S-100（+），波形蛋白（+），SOX-10（+）。GCT 又称 Abrikossoff 肿瘤，是一种罕见的良性肿瘤，较少发生于喉部，尤其在儿童。该病例报道强调，对于喉部颗粒细胞瘤，应高度重视鉴别诊断。鉴于 GCT 的复发风险，术后需长期随访。
