Talamo J H, D'Amico D J, Kenyon K R
Arch Ophthalmol. 1986 Oct;104(10):1483-5. doi: 10.1001/archopht.1986.01050220077030.
Intravitreal administration of broad-spectrum antibiotics is a widely accepted component of initial therapy for bacterial endophthalmitis. Four cases of culture-proved bacterial endophthalmitis are reported to demonstrate the safety of intravitreal administration of amikacin sulfate in conjunction with cephalosporins in patients. The benefits of using amikacin rather than gentamicin sulfate in intravitreal drug therapy are discussed, and a wider role for amikacin as the aminoglycoside of choice for initial intravitreal injection in presumed bacterial endophthalmitis is suggested.
玻璃体内注射广谱抗生素是细菌性眼内炎初始治疗中广泛接受的组成部分。本文报告了4例经培养证实的细菌性眼内炎病例，以证明硫酸阿米卡星与头孢菌素联合玻璃体内注射在患者中的安全性。讨论了在玻璃体内药物治疗中使用阿米卡星而非硫酸庆大霉素的益处，并建议阿米卡星在疑似细菌性眼内炎初始玻璃体内注射中作为首选氨基糖苷类药物发挥更广泛的作用。
