Frenette Brandon L, Rivard Eric
Department of Chemistry, University of Alberta, 11227 Saskatchewan Dr., Edmonton, Alberta, T6G 2G2, Canada.
Chemistry. 2023 Nov 21;29(65):e202302332. doi: 10.1002/chem.202302332. Epub 2023 Oct 19.
Frustrated Lewis pairs (FLPs) have been the subject of considerable study since the field's inception. While much of the research into FLPs has centered around small molecule activation for diverse stoichiometric and catalytic transformations, intramolecular FLPs also show promise as chelating ligands. The cooperative action of Lewis basic and acidic moieties enables intramolecular FLPs to stabilize low oxidation state centers and (consequently) reactive molecular fragments through a donor-acceptor approach, making them an attractive ligand class in main group element chemistry. This review outlines the state of FLP chelation to date throughout the p-block, encompassing primarily groups 13-16.
自该领域创立以来，受阻路易斯酸碱对（FLPs）一直是大量研究的主题。虽然对FLPs的许多研究都集中在用于各种化学计量和催化转化的小分子活化上，但分子内FLPs作为螯合配体也显示出前景。路易斯碱性和酸性部分的协同作用使分子内FLPs能够通过供体-受体方法稳定低氧化态中心以及（因此）反应性分子片段，使其成为主族元素化学中一类有吸引力的配体。本综述概述了迄今为止整个p区（主要包括13-16族）中FLP螯合的状况。
