Division of Gynecologic Oncology and the Department of Radiation Oncology, Stanford University School of Medicine, and the Division of Gynecologic Oncology, California Pacific/Palo Alto/Sutter Health Research Institute, Palo Alto, California; the Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; the Department of Obstetrics & Gynecology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; the California Pacific Medical Center Research Institute, San Francisco, California; and the Gynecologic Cancer Center of Excellence Program, Department of Gynecologic Surgery and Obstetrics, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, and the Henry M. Jackson Foundation for Advancement of Military Medicine, Inc., Bethesda, Maryland.
Obstet Gynecol. 2023 Oct 1;142(4):978-986. doi: 10.1097/AOG.0000000000005321. Epub 2023 Sep 7.
To analyze mortality trends in uterine cancer in the United States over 50 years with an emphasis on age and race and ethnicity.
Data on uterine cancer deaths from 1969 to 2018 were obtained from the National Center for Health Statistics. Trends were examined by age and race and ethnicity after adjustment for the hysterectomy rate and pregnancy.
Uterine cancer mortality decreased between 1969 and 1997 (from 6.03 to 4.00/100,000) but increased between 1997 and 2018 (from 4.00 to 5.02/100,000). From 2001 to 2018, mortality rates increased by 1.25-fold across all age groups. In 2018, the mortality rate from uterine cancer for patients aged 70 years or older and 60-69 years was sixfold and threefold higher, respectively, than in younger patients (aged 50-59 years) (54.87/100,000 vs 27.80/100,000 vs 8.70/100,000). The mortality rate for non-Hispanic Black women was 2.2-fold higher than for non-Hispanic White, Hispanic, and non-Hispanic Asian or Pacific Islander women (17.6/100,000 vs 7.82/100,000, 6.54/100,000, and 4.24/100,000, respectively). On an intersection analysis of age and race, non-Hispanic Black women aged older than 60 years had a threefold higher mortality rate than non-Hispanic White women (72/100,000 vs 24/100,000). A notable finding was that young non-Hispanic Black and Hispanic women (30-39 years) had the highest annual increases in mortality at 3.3% and 3.8% per year compared with 2.2% in non-Hispanic White women.
Since 2001, the uterine cancer mortality rate has increased across all four racial and ethnic groups examined, with the highest increase seen among non-Hispanic Black women. The largest increase in mortality was observed among younger non-Hispanic Black and Hispanic women.
分析美国 50 多年来子宫癌死亡率的趋势，重点关注年龄、种族和民族。
从国家卫生统计中心获取 1969 年至 2018 年子宫癌死亡数据。在调整子宫切除术率和妊娠率后，按年龄和种族和民族进行趋势分析。
1969 年至 1997 年，子宫癌死亡率从 6.03/10 万下降至 4.00/10 万，但 1997 年至 2018 年又上升至 5.02/10 万。从 2001 年到 2018 年，所有年龄组的死亡率增加了 1.25 倍。2018 年，70 岁及以上和 60-69 岁的子宫癌患者死亡率分别是非 50-59 岁患者的 6 倍和 3 倍（54.87/10 万比 27.80/10 万比 8.70/10 万）。非西班牙裔黑人女性的死亡率是非西班牙裔白人、西班牙裔和非西班牙裔亚裔或太平洋岛民女性的 2.2 倍（17.6/10 万比 7.82/10 万、6.54/10 万和 4.24/10 万）。在年龄和种族的交叉分析中，60 岁以上的非西班牙裔黑人女性的死亡率是非西班牙裔白人女性的 3 倍（72/10 万比 24/10 万）。一个值得注意的发现是，年轻的非西班牙裔黑人女性（30-39 岁）和西班牙裔女性的死亡率每年以 3.3%和 3.8%的速度增长，而非西班牙裔白人女性为 2.2%。
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