John Sealy School of Medicine, University of Texas Medical Branch, Galveston, TX, USA.
Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA.
Am J Surg. 2024 Oct;236:115427. doi: 10.1016/j.amjsurg.2023.08.015. Epub 2023 Aug 24.
Post-burn pruritus (PBP) has been shown to adversely affect burn patients' quality of life. However, the predictors of PBP are not known. We hypothesize a pre-existing pruritic skin diagnosis is associated with an increased risk of adverse outcomes following a burn injury.
This retrospective study utilized data from the TriNetX electronic health record. Burn patients with a history of a pruritic skin disorder were compared to patients without a diagnosed skin disorder and the occurrence of pruritus was compared between the two cohorts.
Patients with pre-existing skin conditions were more likely to develop PBP. The risk of PBP was highest 1 year after injury. Stratification by percent TBSA burned, gender, race, and age showed an increased risk of PBP for females, Caucasians, older patients, and those with large burns.
A pre-existing pruritic skin diagnosis is highly associated with developing pruritus following a burn injury.
烧伤后瘙痒（PBP）已被证明会对烧伤患者的生活质量产生不利影响。然而，PBP 的预测因素尚不清楚。我们假设，在烧伤损伤后，先前存在的瘙痒性皮肤诊断与不良结局的风险增加相关。
本回顾性研究利用了来自 TriNetX 电子健康记录的数据。将有瘙痒性皮肤疾病史的烧伤患者与无诊断性皮肤疾病的患者进行比较，并比较了两组之间瘙痒的发生情况。
患有先前存在的皮肤疾病的患者更有可能出现 PBP。受伤后 1 年发生 PBP 的风险最高。按烧伤总面积百分比、性别、种族和年龄分层显示，女性、白种人、老年患者和大面积烧伤患者发生 PBP 的风险增加。
先前存在的瘙痒性皮肤诊断与烧伤后出现瘙痒高度相关。
