Riviere G R, Tarbox G S
J Oral Surg. 1979 Jul;37(7):477-81.
The genetic and immunologic criteria required for successful tooth transplantation have yet to be defined. Teeth grafted across strong barriers elicit vigorous immunity. However, teeth and tooth germs transplanted to subcutaneous sites in H-2 compatible but multiple-non-H-2 disparate recipients stimulated weak in vitro cellular cytotoxicity compared with skin grafts 5 mm in diameter. Furthermore, tooth allografts did not sensitize recipients as measured by the rejection of second-set, donor skin grafts. It may be that tooth allografts provoke fewer detrimental immune mediator systems than do skin grafts across moderate to weak transplantation barriers.
成功进行牙齿移植所需的遗传和免疫学标准尚未明确。跨越强大屏障移植的牙齿会引发强烈的免疫反应。然而，与直径5毫米的皮肤移植相比，移植到H-2相容但多个非H-2不匹配受体皮下部位的牙齿和牙胚在体外刺激的细胞毒性较弱。此外，通过二次移植供体皮肤移植物的排斥反应测量，牙齿同种异体移植物不会使受体致敏。可能是牙齿同种异体移植物引发的有害免疫介质系统比跨越中度至弱移植屏障的皮肤移植物少。
