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Secondary-type mutations do not impact outcome in NPM1-mutated acute myeloid leukemia - implications for the European LeukemiaNet risk classification.

作者信息

Eckardt Jan-Niklas, Bill Marius, Rausch Christian, Metzeler Klaus, Spiekermann Karsten, Stasik Sebastian, Sauer Tim, Scholl Sebastian, Hochhaus Andreas, Crysandt Martina, Brümmendorf Tim H, Krug Utz, Wörmann Bernhard, Hiddemann Wolfgang, Görlich Dennis, Sauerland Cristina, Steffen Björn, Einsele Hermann, Neubauer Andreas, Burchert Andreas, Schäfer-Eckart Kerstin, Berdel Wolfgang E, Schliemann Christoph, Krause Stefan W, Hänel Mathias, Hanoun Maher, Kaufmann Martin, Fransecky Lars, Braess Jan, Ruhnke Leo, Schetelig Johannes, Middeke Jan Moritz, Serve Hubert, Baldus Claudia D, Platzbecker Uwe, Müller-Tidow Carsten, Bornhäuser Martin, Herold Tobias, Thiede Christian, Röllig Christoph

机构信息

Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.

Mildred Scheel Early Career Center, Medical Clinic and Policlinic I, University Hospital of the Technical University Dresden, Dresden, Germany.

出版信息

Leukemia. 2023 Nov;37(11):2282-2285. doi: 10.1038/s41375-023-02016-6. Epub 2023 Sep 7.

DOI:10.1038/s41375-023-02016-6
PMID:37679502
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10624615/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/416d/10624615/f972c7635fcc/41375_2023_2016_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/416d/10624615/f972c7635fcc/41375_2023_2016_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/416d/10624615/f972c7635fcc/41375_2023_2016_Fig1_HTML.jpg

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Blood. 2023 Apr 13;141(15):1846-1857. doi: 10.1182/blood.2022018108.
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Revisiting coexisting chromosomal abnormalities in NPM1-mutated AML in light of the revised ELN 2022 classification.根据2022年修订的欧洲白血病网络（ELN）分类重新审视NPM1突变型急性髓系白血病（AML）中共存的染色体异常
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