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人体红细胞中氧化型谷胱甘肽和S-二硝基苯谷胱甘肽不同转运系统的证据。

Evidence for different transport systems for oxidized glutathione and S-dinitrophenyl glutathione in human erythrocytes.

作者信息

LaBelle E F, Singh S V, Srivastava S K, Awasthi Y C

出版信息

Biochem Biophys Res Commun. 1986 Sep 14;139(2):538-44. doi: 10.1016/s0006-291x(86)80024-9.

DOI:10.1016/s0006-291x(86)80024-9
PMID:3767975
Abstract

The effect of oxidized glutathione (GSSG) on the ATP-dependent transport of S-dinitrophenyl glutathione (Dnp-SG) by inside-out vesicles prepared from human erythrocytes and by intact erythrocytes has been studied. It is demonstrated that the transport of Dnp-SG is not inhibited by GSSG in either intact erythrocytes or in inside-out vesicles. These results suggest that Dnp-SG and GSSG are transported out of human erythrocytes by separate systems.

摘要

研究了氧化型谷胱甘肽(GSSG)对由人红细胞制备的内翻囊泡以及完整红细胞中S - 二硝基苯基谷胱甘肽(Dnp - SG)的ATP依赖性转运的影响。结果表明,在完整红细胞或内翻囊泡中,GSSG均不抑制Dnp - SG的转运。这些结果提示,Dnp - SG和GSSG通过不同的系统从人红细胞中转运出去。

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Evidence for different transport systems for oxidized glutathione and S-dinitrophenyl glutathione in human erythrocytes.人体红细胞中氧化型谷胱甘肽和S-二硝基苯谷胱甘肽不同转运系统的证据。
Biochem Biophys Res Commun. 1986 Sep 14;139(2):538-44. doi: 10.1016/s0006-291x(86)80024-9.
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