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精索脂肪肉瘤:现状与我们的经验

Liposarcoma of the spermatic cord: The state of art and our experience.

作者信息

Di Pilla Maria Antonietta, Capuano Marco Alex, Rossi Mariangela, Di Pilla Gianni, Minelli Rocco, Pizzicato Paolo, Rossi Antonio, Paviglianiti Giuseppe, Irace Donatella, Vallone Gianfranco, Salvia Antonio A H, Smaldone Maria Cristina, Cariello Valentina, Zeccolini Raffaele, Rossi Eugenio

机构信息

Life and Health Department "V. Tiberio", University of Molise, Campobasso, Italy.

Department of Radiodiagnostics "F. Veneziale", Molise Regional HealthCompany (ASREM), Isernia, Italy.

出版信息

Radiol Case Rep. 2023 Aug 30;18(11):3941-3944. doi: 10.1016/j.radcr.2023.08.031. eCollection 2023 Nov.

DOI:10.1016/j.radcr.2023.08.031
PMID:37680656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10480435/
Abstract

Liposarcoma of the spermatic cord is a malignant neoformation so rare that less than 200 cases are reported in the world. It is a tumor that originates from adipose tissue and when it is found in the spermatic cord it can deceptively simulate an inguinal hernia and not be easily identified. The present work describes the case of a 37-year-old man with liposarcoma of the spermatic cord who arrives at our institution with painless swelling of the left testicle. Physical examination revealed a painless swelling in the scrotal sac. The scrotal ultrasound examination revealed a mass, measuring 8 cm (cranio-caudal) × 5.4 cm (latero-lateral) × 8 cm (antero-posterior) and characterized later with a basal CT examination of the abdomen. The patient was subsequently surgically treated with excision of the tumor, plus hernial plastic with plug and mesh. Histological examination revealed a mature adipocyte neoplasm whose morphological and molecular characteristics (amplification of the MDM2 gene) are consistent with the diagnosis of . The patient is currently under cancer surveillance with no signs of loco-regional recurrence. Spermatic cord liposarcoma is an extremely rare malignancy. It's not easy to identify as it can simulate an inguinal hernia, hydrocele, lipoma, funicular cyst, or testicular tumor. Diagnosis is usually established postsurgery, however, relapses are common and the role of chemo-radiotherapy remains to be defined.

摘要

精索脂肪肉瘤是一种极为罕见的恶性新生物,全球报道的病例不足200例。它是一种起源于脂肪组织的肿瘤,当出现在精索时,可能会误导性地模拟腹股沟疝,不易被识别。本文描述了一名37岁患有精索脂肪肉瘤的男性病例,他因左侧睾丸无痛性肿胀前来我院就诊。体格检查发现阴囊内有无痛性肿胀。阴囊超声检查发现一个肿块,大小为8厘米(头-尾径)×5.4厘米(外侧径)×8厘米(前后径),随后通过腹部增强CT检查进一步明确特征。该患者随后接受了肿瘤切除手术,并进行了疝修补术,使用补片和网塞。组织学检查显示为成熟脂肪细胞肿瘤,其形态学和分子特征(MDM2基因扩增)与诊断相符。该患者目前正在接受癌症监测,无局部复发迹象。精索脂肪肉瘤是一种极其罕见的恶性肿瘤。由于它可以模拟腹股沟疝、鞘膜积液、脂肪瘤、精索囊肿或睾丸肿瘤,因此不易识别。诊断通常在手术后确立,然而,复发很常见,化疗和放疗的作用仍有待确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f89/10480435/ec7d26843439/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f89/10480435/ea083ce9dbdd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f89/10480435/05645a4851b5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f89/10480435/ec7d26843439/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f89/10480435/ea083ce9dbdd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f89/10480435/05645a4851b5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f89/10480435/ec7d26843439/gr3.jpg

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本文引用的文献

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Liposarcoma of the Spermatic Cord Mimicking an Inguinal Hernia: A Case Report and Literature Review.精索脂肪肉瘤酷似腹股沟疝:一例报告及文献复习
Cureus. 2022 Aug 22;14(8):e28269. doi: 10.7759/cureus.28269. eCollection 2022 Aug.
2
LIPOSARCOMA OF THE SPERMATIC CORD - DIAGNOSTIC AND THERAPEUTIC ISSUE.精索脂肪肉瘤——诊断与治疗问题。
Acta Clin Croat. 2021 Mar;60(1):50-54. doi: 10.20471/acc.2021.60.01.07.
3
Well-differentiated liposarcoma of the spermatic cord: A case report.精索高分化脂肪肉瘤:一例报告
Urol Case Rep. 2021 Jan 29;36:101587. doi: 10.1016/j.eucr.2021.101587. eCollection 2021 May.
4
A rare case of liposarcoma of the spermatic cord.一例罕见的精索脂肪肉瘤。
Urol Case Rep. 2020 Jul 6;33:101336. doi: 10.1016/j.eucr.2020.101336. eCollection 2020 Nov.
5
Liposarcoma of the spermatic cord presenting as an inguinal hernia.表现为腹股沟疝的精索脂肪肉瘤。
Int J Surg Case Rep. 2020;76:274-277. doi: 10.1016/j.ijscr.2020.09.195. Epub 2020 Oct 2.
6
Dedifferentiated liposarcoma of the spermatic cord: Case report and review of literature.精索去分化脂肪肉瘤:病例报告及文献复习
Int J Surg Case Rep. 2020;72:418-422. doi: 10.1016/j.ijscr.2020.06.051. Epub 2020 Jun 12.
7
Current management of liposarcoma of the spermatic cord: A case report and review of the literature.精索脂肪肉瘤的当前管理:一例病例报告及文献综述。
Mol Clin Oncol. 2017 Mar;6(3):438-440. doi: 10.3892/mco.2017.1157. Epub 2017 Feb 6.
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Liposarcoma of the spermatic cord: a diagnostic dilemma.精索脂肪肉瘤:诊断难题。
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