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感染——来自希腊一家三级医院的病例系列

infection - a case series from a tertiary hospital in Greece.

作者信息

Ioannou Petros, Karakonstantis Stamatis, Tavlas Emmanuil, Kontopodis Nikolaos, Maraki Sofia, Chamilos George, Kofteridis Diamantis P

机构信息

MD, MSc, PhD, Department of Internal Medicine, University Hospital of Heraklion, Crete, Greece, Stavrakia and Voutes crossroads, Heraklion, Crete, Greece, PC 71110.

MD, MSc, Department of Vascular Diseases, University Hospital of Heraklion, Crete, Greece, Stavrakia and Voutes crossroads, Heraklion, Crete, Greece, PC 71110.

出版信息

Germs. 2022 Sep 30;12(3):394-399. doi: 10.18683/germs.2022.1343. eCollection 2022 Sep.

Abstract

INTRODUCTION

is a small Gram-positive facultative anaerobic coccoid rod that was reclassified in 1997 from the genus and is difficult to culture with usual microbiological techniques, as it is slowly growing. is an emerging human pathogen that is most commonly implicated in urinary tract infections (UTIs), but has also been isolated less frequently from abscesses of various sites (such as the skin, the genitourinary tract, surgical sites or intraabdominal).

METHODS

All cases where was identified during a 6-year period (January 2016 - January 2022) in the University Hospital of Heraklion were reviewed.

RESULTS

was isolated in 11 cultures from 10 patients. The site of infection was skin and soft tissue in nine out of eleven cultures (81.8%) and the bone was the site of infection in two patients (18.2%). Most cultures were polymicrobial. The median age of patients was 55.5 years (interquartile range 34-63 years), and 80% (n=8) were male. was susceptible to beta-lactams, quinolones and vancomycin, but resistant to clindamycin, erythromycin and metronidazole. Moreover, two cases of diabetic patients diagnosed with polymicrobial diabetic foot osteomyelitis from this organism are presented in detail. Both patients were successfully managed with targeted antimicrobial treatment and prompt surgical management.

CONCLUSIONS

is an emerging pathogen that is likely under-reported due to difficulties in isolation and identification. Herein two cases of diabetic foot osteomyelitis are also presented in detail, successfully managed with targeted antimicrobial therapy and surgical debridement.

摘要

引言

[具体细菌名称未给出]是一种革兰氏阳性兼性厌氧球杆状菌,于1997年从[相关属名未给出]属重新分类,由于生长缓慢,用常规微生物技术难以培养。[具体细菌名称未给出]是一种新出现的人类病原体,最常与尿路感染(UTIs)有关,但也较少从各个部位的脓肿(如皮肤、泌尿生殖道、手术部位或腹腔内)分离出来。

方法

回顾了在伊拉克利翁大学医院6年期间(2016年1月至2022年1月)所有鉴定出[具体细菌名称未给出]的病例。

结果

从10名患者的11份培养物中分离出[具体细菌名称未给出]。11份培养物中有9份(81.8%)的感染部位是皮肤和软组织,2名患者(18.2%)的感染部位是骨骼。大多数培养物是混合菌感染。患者的中位年龄为55.5岁(四分位间距34 - 63岁),80%(n = 8)为男性。[具体细菌名称未给出]对β - 内酰胺类、喹诺酮类和万古霉素敏感,但对克林霉素、红霉素和甲硝唑耐药。此外,详细介绍了2例被诊断为由该病原体引起的混合菌性糖尿病足骨髓炎的糖尿病患者。两名患者均通过针对性抗菌治疗和及时的手术治疗成功治愈。

结论

[具体细菌名称未给出]是一种新出现的病原体,由于分离和鉴定困难,可能报告不足。本文还详细介绍了2例糖尿病足骨髓炎病例,通过针对性抗菌治疗和手术清创成功治愈。

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