Kakodkar Pramath, Hamula Camille
Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 0W8, Canada.
Microorganisms. 2022 Aug 9;10(8):1608. doi: 10.3390/microorganisms10081608.
(1) Background: is an emerging, opportunistic pathogen often linked with UTIs but can extend beyond the urogenital system. Data on the clinical significance of are still emerging. (2) Methods: A retrospective review of isolates in a Canadian tertiary care hospital was conducted. The clinical data of patients that grew from January 2020 to 2022 were documented. Demographics, site, management, and microbiological parameters surrounding culture and sensitivities were recorded. (3) Results: A total of 43 cases of were identified. was primarily involved in UTIs ( = 17), abscesses ( = 9), bacteremia ( = 6), septic arthritis ( = 5), and ulcers ( = 5). had a slight predilection for polymicrobial infections (51.1%, = 22 out of 43), with ( = 5) being the most common coisolate. Susceptibility testing was only performed in two cases that showed sensitivity to beta-lactam antibiotics and resistance to metronidazole and ciprofloxacin. Amoxicillin-clavulanate ( = 5) is the most frequently prescribed antibiotic. (4) Conclusions: The non-urogenic clinical significance of remains undervalued. The management of infection is multimodal, consisting predominantly of antimicrobials and surgical procedures specific to the etiology. Clinicians should request sensitivities for so that appropriate antimicrobial coverage can be provided.
(1) 背景:[病原体名称]是一种新兴的机会性病原体,常与尿路感染相关,但可超出泌尿生殖系统范围。关于[病原体名称]临床意义的数据仍在不断涌现。(2) 方法:对加拿大一家三级护理医院的[病原体名称]分离株进行回顾性研究。记录了2020年1月至2022年培养出[病原体名称]的患者的临床数据。记录了人口统计学、感染部位、治疗方法以及围绕培养和药敏的微生物学参数。(3) 结果:共鉴定出43例[病原体名称]感染病例。[病原体名称]主要涉及尿路感染(n = 17)、脓肿(n = 9)、菌血症(n = 6)、化脓性关节炎(n = 5)和溃疡(n = 5)。[病原体名称]对混合感染有轻微偏好(51.1%,43例中有22例),其中[常见共分离病原体名称](n = 5)是最常见的共分离病原体。仅对2例进行了药敏试验,结果显示对β-内酰胺类抗生素敏感,对甲硝唑和环丙沙星耐药。阿莫西林-克拉维酸(n = 5)是最常使用的抗生素。(4) 结论:[病原体名称]的非泌尿源性临床意义仍未得到充分重视。[病原体名称]感染的治疗是多模式的,主要包括针对病因的抗菌药物和外科手术。临床医生应要求对[病原体名称]进行药敏试验,以便提供适当的抗菌药物覆盖。