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Germs. 2022 Sep 30;12(3):409-413. doi: 10.18683/germs.2022.1346. eCollection 2022 Sep.
2
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Rev Esp Patol. 2018 Oct-Dec;51(4):253-256. doi: 10.1016/j.patol.2017.10.005. Epub 2017 Dec 6.
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本文引用的文献

1
bacteraemia associated with cervical and mediastinal abscesses in an immunocompetent patient: First reported case in Qatar.免疫功能正常患者中与颈部和纵隔脓肿相关的菌血症:卡塔尔首例报告病例。
New Microbes New Infect. 2022 Jan 17;45:100956. doi: 10.1016/j.nmni.2022.100956. eCollection 2022 Jan.
2
Mediastinal Actinomycosis After Esophagogastroduodenoscopy.食管胃十二指肠镜检查术后纵隔放线菌病
Cureus. 2020 Jun 3;12(6):e8423. doi: 10.7759/cureus.8423.
3
Unusual aetiology of lymphocyte-predominant exudative pleural effusion: primary mediastinal actinomycosis.淋巴细胞为主型渗出性胸腔积液的罕见病因:原发性纵隔放线菌病。
Respirol Case Rep. 2020 Feb 14;8(3):e00534. doi: 10.1002/rcr2.534. eCollection 2020 Apr.
4
Actinomycosis: a frequently forgotten disease.放线菌病:一种常被遗忘的疾病。
Future Microbiol. 2015;10(4):613-28. doi: 10.2217/fmb.14.130.
5
Actinomycosis: etiology, clinical features, diagnosis, treatment, and management.放线菌病:病因、临床特征、诊断、治疗和管理。
Infect Drug Resist. 2014 Jul 5;7:183-97. doi: 10.2147/IDR.S39601. eCollection 2014.
6
Mediastinitis by Actinomyces meyeri after oesophageal stent placement.食管支架置入术后迈耶放线菌引起的纵隔炎
BMJ Case Rep. 2014 Jun 5;2014:bcr2014204499. doi: 10.1136/bcr-2014-204499.
7
An unusual cause of superior vena cava syndrome.上腔静脉综合征的一种罕见病因。
Indian J Med Res. 2012 Aug;136(2):312.
8
Medical management of pulmonary actinomycosis: data from 49 consecutive cases.肺放线菌病的药物治疗:49例连续病例的数据。
J Antimicrob Chemother. 2009 Apr;63(4):839-41. doi: 10.1093/jac/dkp016. Epub 2009 Feb 13.
9
Multicenter evaluation of the Vitek 2 anaerobe and Corynebacterium identification card.Vitek 2厌氧菌及棒状杆菌鉴定卡的多中心评估
J Clin Microbiol. 2008 Aug;46(8):2646-51. doi: 10.1128/JCM.00450-08. Epub 2008 Jun 18.
10
Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents.用12种抗菌剂对放线菌属进行药敏试验。
J Antimicrob Chemother. 2005 Aug;56(2):407-9. doi: 10.1093/jac/dki206. Epub 2005 Jun 21.

在纵隔内。惊喜是所有艺术的关键。

in the mediastinum. Surprise is key in all art.

作者信息

Severiche-Bueno Diego Fernando, Ramirez Sandra Ximena, Vargas-Cuervo María Teresa, Bueno David Felipe Severiche, Navarro Carmelo Jiménez, Mugnier Jacqueline, Rodriguez Juan Pablo

机构信息

MD, MSc, Universidad de La Sabana, Chía, Cundinamarca, KM 7.5 Autopista Norte de Bogotá, Chía, Colombia.

MD, Universidad del Rosario, Bogotá D.C, Colombia, Calle 163A # 13B - 60 Bogotá, Colombia.

出版信息

Germs. 2022 Sep 30;12(3):409-413. doi: 10.18683/germs.2022.1346. eCollection 2022 Sep.

DOI:10.18683/germs.2022.1346
PMID:37680682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10482480/
Abstract

INTRODUCTION

Actinomycosis is an unusual chronic granulomatous infectious disease. They are commensals in various sites of the human body but with little pathogenicity. is the most prevalent species but more than 30 species have been described. Infection of the lower respiratory tract is unusual, the involvement of mediastinum being even rarer.

CASE REPORT

A 63-year-old man, previously healthy and living in a rural area, presented with a 5-month history of hemoptysis, pleuritic pain, weight loss, and night sweats. Community-acquired pneumonia with a mediastinal mass was documented, for which he received antibiotic management. Thoracoscopy was carried out for diagnosis and resection of the mediastinal mass due to inconclusive findings in the percutaneous biopsy. Pathology reported the presence of filamentous Gram-positive bacteria visible in Grocott staining. Due to the pathology findings, and the fact that no other infectious agents were identified, a diagnosis of actinomycosis was established. Treatment with oral amoxicillin 1g TID for 6 months was initiated.

CONCLUSIONS

As far as we are aware, we present the sixth case of mediastinal actinomycosis. We present this case to bring attention to this rare but clinically relevant presentation to be considered as a differential diagnosis of mediastinal masses and to emphasize the need for specific anaerobic cultures to improve the diagnostic yield.

摘要

引言

放线菌病是一种罕见的慢性肉芽肿性传染病。它们是人体各个部位的共生菌,但致病性很低。放线菌是最常见的菌种,但已描述的菌种超过30种。下呼吸道感染并不常见,纵隔受累更为罕见。

病例报告

一名63岁男性,既往健康,居住在农村地区,出现咯血、胸膜炎性疼痛、体重减轻和盗汗5个月。记录为社区获得性肺炎伴纵隔肿块,为此他接受了抗生素治疗。由于经皮活检结果不明确,进行了胸腔镜检查以诊断和切除纵隔肿块。病理报告在格罗科特染色中可见丝状革兰氏阳性菌。由于病理结果以及未发现其他感染病原体,确诊为放线菌病。开始口服阿莫西林1g,每日三次,治疗6个月。

结论

据我们所知,我们报告的是第六例纵隔放线菌病。我们报告此病例是为了引起对这种罕见但临床上相关表现的关注,将其作为纵隔肿块的鉴别诊断加以考虑,并强调需要进行特定的厌氧菌培养以提高诊断率。