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使用低剂量阴道米索前列醇引产的女性的母婴结局

Maternal and fetal outcomes in women undergoing induction of labor with low dose vaginal misoprostol.

作者信息

Shafqat Tanveer, Zeb Laila, Fatima Syeda Sitwat, Bhittani Rehana

机构信息

Tanveer Shafqat, FCPS (Obstet & Gynae) Associate Professor, Department of Obstetrics and Gynaecology, Medical Teaching Institute, Lady Reading Hospital, Peshawar, Pakistan.

Laila Zeb, FCPS (Obstet & Gynae) Assistant Professor, Department of Obstetrics and Gynaecology, Medical Teaching Institute, Lady Reading Hospital, Peshawar, Pakistan.

出版信息

Pak J Med Sci. 2023 Sep-Oct;39(5):1307-1311. doi: 10.12669/pjms.39.5.7072.

Abstract

OBJECTIVE

To determine Maternal and Fetal outcome in women undergoing induction of labour with low dose misoprostol.

METHOD

A cross-sectional study was carried out to determine the efficacy of Misoprostol for induction of labor (IOL) in MTI, Lady Reading Hospital (LRH), Peshawar from 21st January to 31st December 2021. All pregnant women with singleton pregnancy and cephalic presentation admitted for Induction of Labor were included in the study. Maternal and Fetal outcome was noted. Induction of labor was started with 25 micrograms of Misoprostol, repeated every six hours depending on Bishop Score.

RESULTS

Three hundred and thirty-seven women were included in this study. The majority of females (76%) were in 18-35 years age group. In 92.3% of females, the Bishop score was less than six. The maximum number of females (33.5%) delivered after eight hours of IOL. Sixty-six (66.46%) of females had gestational age of 37-40 weeks. Premature rupture of membranes was the most common indication (32.9%). Three doses of misoprostol were required in 31.2% of females. Only 5.6% of females required six doses of misoprostol for induction. With Misoprostol 85.1% of females delivered spontaneously, 2.37% required forceps delivery, 1.7% required vacuum delivery, and 10.68% delivered by Caesarean Section. APGAR score was 8 /10 in 84% of neonates at birth. Eighty-seven %(87.8%) of neonates did not require NICU admission.

CONCLUSION

Misoprostol is a safe medicine to be used to induce labor in females. It can help shorten the duration of labor, with good fetomaternal outcome.

摘要

目的

确定使用低剂量米索前列醇引产的产妇和胎儿结局。

方法

于2021年1月21日至12月31日在白沙瓦市雷丁夫人医院(LRH)的MTI进行了一项横断面研究,以确定米索前列醇用于引产(IOL)的疗效。所有因引产入院的单胎妊娠且头先露的孕妇均纳入研究。记录产妇和胎儿结局。引产起始剂量为25微克米索前列醇,根据 Bishop 评分每6小时重复给药一次。

结果

本研究纳入了337名女性。大多数女性(76%)年龄在18 - 35岁组。92.3%的女性 Bishop 评分小于6分。最大比例的女性(33.5%)在引产8小时后分娩。66名(66.46%)女性的孕周为37 - 40周。胎膜早破是最常见的指征(32.9%)。31.2%的女性需要三剂米索前列醇。仅5.6%的女性引产需要六剂米索前列醇。使用米索前列醇后,85.1%的女性自然分娩,2.37%需要产钳助产,1.7%需要真空吸引助产,10.68%通过剖宫产分娩。出生时84%的新生儿阿氏评分是8/10。87.8%的新生儿不需要入住新生儿重症监护病房(NICU)。

结论

米索前列醇是用于女性引产的一种安全药物。它有助于缩短产程,母婴结局良好。

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本文引用的文献

1
Misoprostol for labour induction.米索前列醇用于引产。
Best Pract Res Clin Obstet Gynaecol. 2021 Nov;77:53-63. doi: 10.1016/j.bpobgyn.2021.09.003. Epub 2021 Sep 15.
4
Induction of Labor: An Overview of Guidelines.引产:指南概述。
Obstet Gynecol Surv. 2020 Jan;75(1):61-72. doi: 10.1097/OGX.0000000000000752.

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