Lewandowski A, Kozaczek W, Orlowski T, Weuta H
Arzneimittelforschung. 1986 Jul;36(7):1148-50.
Ten patients with pyelonephritis and impaired renal function were treated with 2.0 g mezlocillin (Baypen) 8-hourly. They all recovered from urinary tract infection and showed a distinct improvement of their kidney function measured by blood urea nitrogen, serum creatinine and creatinine clearance. No side effects were seen and the blood coagulation remained within normal limits. An overview of the literature on urinary tract infections treated in patients with impaired kidney function is given.
10名患有肾盂肾炎且肾功能受损的患者接受了美洛西林（拜朋）治疗，剂量为2.0克，每8小时一次。他们均从尿路感染中康复，通过血尿素氮、血清肌酐和肌酐清除率测量显示肾功能有明显改善。未观察到副作用，血液凝固仍在正常范围内。本文还对肾功能受损患者尿路感染的文献进行了综述。
