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一次性使用软性输尿管镜治疗上尿路结石:系统评价和荟萃分析。

Single-use flexible ureteroscope provides an alternative treatment for upper urinary calculi: A systematic review and meta-analysis.

机构信息

Department of Urology, People's Hospital of Longhua, Southern Medical University, Shenzhen, China.

Department of Urology, Guangzhou, China.

出版信息

Medicine (Baltimore). 2023 Sep 8;102(36):e34829. doi: 10.1097/MD.0000000000034829.

Abstract

OBJECTIVE

This study aimed to evaluate the efficacy and safety of single-use flexible ureteroscope and reusable flexible ureteroscope for upper urinary calculi.

METHODS

We conducted a meta-analysis that had a comprehensive search in PubMed, Embase, Cochrane Library, Web of Science, and WanFang databases from 2000/01/01 to 2023/06/01 for available randomized controlled trials. "Ureteroscopes," "Flexible Ureteroscope," "Single-use," and "Upper Urinary Calculi" were used as the major keywords for the search. Review Manager 5.0 and STATA 12.0 were used for calculation and statistical analysis.

RESULTS

A total of 9 randomized controlled trials comprising 1293 participants were included in our meta-analysis. Single use-FURS had better results in stone-free rate (relative risk: 1.08, 95% confidence interval: [1.02, 1.15], P = .02) and postoperative infection (relative risk: 0.41, 95% confidence interval: [0.23, 0.72], P = .002). Operative time, hemoglobin decline, postoperative serum creatinine, postoperative hospital stay, and overall complication after surgery showed no significant differences between the 2 procedures (P > .05).

CONCLUSION

Single-use flexible ureteroscope provides a valuable alternative to reusable flexible ureteroscope in upper urinary calculi with its better visual field performance and manipulation, opening a new technological revolution for kidney stone treatment.

摘要

目的

本研究旨在评估一次性使用输尿管软镜和可重复使用输尿管软镜治疗上尿路结石的疗效和安全性。

方法

我们进行了一项荟萃分析,全面检索了 2000 年 1 月 1 日至 2023 年 6 月 1 日期间的 PubMed、Embase、Cochrane 图书馆、Web of Science 和万方数据库中的可用随机对照试验。“输尿管镜”、“输尿管软镜”、“一次性使用”和“上尿路结石”被用作主要的搜索关键词。使用 Review Manager 5.0 和 STATA 12.0 进行计算和统计分析。

结果

共有 9 项随机对照试验,包括 1293 名参与者,纳入了我们的荟萃分析。一次性使用输尿管软镜在结石清除率方面具有更好的效果(相对风险:1.08,95%置信区间:[1.02,1.15],P =.02)和术后感染(相对风险:0.41,95%置信区间:[0.23,0.72],P =.002)。手术时间、血红蛋白下降、术后血清肌酐、术后住院时间和术后总体并发症在两种手术方法之间没有显著差异(P >.05)。

结论

一次性使用输尿管软镜在上尿路结石治疗中提供了一种比可重复使用输尿管软镜更有价值的选择,其具有更好的视野性能和操作性能,为肾结石治疗开辟了新的技术革命。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a3d/10489268/a4d65d7a3f2f/medi-102-e34829-g001.jpg

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