非规范角色：Hippo 通路调节剂 MAP4K2 在能量应激时控制自噬和细胞存活。
A non-canonical role: The Hippo pathway regulator MAP4K2 controls autophagy and cell survival upon energy stress.
机构信息
Cellular Degradation Systems Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
出版信息
Mol Cell. 2023 Sep 7;83(17):3043-3045. doi: 10.1016/j.molcel.2023.08.020.
PMID:37683608
Abstract
In this issue, Seo et al. report a non-canonical function of the Hippo kinase MAP4K2 in energy stress response by regulating autophagy and cell survival, with relevance and therapeutic potential for head and neck cancer treatment.
摘要
在本期杂志中，Seo 等人报道了 Hippo 激酶 MAP4K2 通过调节自噬和细胞存活在能量应激反应中的非经典功能，这与头颈部癌症治疗的相关性和治疗潜力有关。
Zotero 插件