Kalashnikova M M, Kazanskaia N I
Biull Eksp Biol Med. 1986 Oct;102(10):485-8.
It is known that the bile canaliculus in the liver of almost all vertebrates is made up of membranes of two or more adjacent liver cells. Studying the liver cell ultrastructure of lasting and fed grass carp and silver carp, it was demonstrated that a bile canaliculus is formed by deep invagination of a cell membrane of one hepatocyte. The membrane forms microvilli along the bile canaliculus. The bile canaliculus is seen in the centre of liver cell cytoplasm on the cross section and stretches from the centre of the liver cell cytoplasm to the cell membrane on the longitudinal section. The bile canaliculus is connected with a small duct cell, which is distinct from a liver cell in its small size, little amount of cell organelles and the presence of cytoplasmic filaments. The terminal part of the biliary tract consists of one liver cell and one bile duct cell. The part of the tract adjacent to the terminal one is composed of two or three small bile duct cells devoid of basal membrane. Thus, the liver parenchyma is constituted of a net of numerous bile ducts. In the portal tract, there is a large bile duct, consisting of 12-13 bile duct cells, surrounded by basal membrane and connective tissue cells.
已知几乎所有脊椎动物肝脏中的胆小管是由两个或更多相邻肝细胞的膜组成。通过对长期摄食的草鱼和鲢鱼肝细胞超微结构的研究表明，胆小管是由一个肝细胞的细胞膜向内深陷形成的。该膜沿胆小管形成微绒毛。在横切面上，胆小管位于肝细胞质的中央，在纵切面上则从肝细胞质的中央延伸至细胞膜。胆小管与一个小胆管细胞相连，该小胆管细胞在大小、细胞器数量和存在细胞质细丝方面与肝细胞不同。胆道的末端部分由一个肝细胞和一个胆管细胞组成。与末端相邻的部分由两三个无基底膜的小胆管细胞组成。因此，肝实质由众多胆管组成的网络构成。在门管区，有一条由12 - 13个胆管细胞组成的大胆管，周围有基底膜和结缔组织细胞。
