Gasch-Illescas Antonia, Andrade-Arroyo María, Vallejo-Vaz Antonio J, Praena-Fernández Juan M, Guerrero José A, Calderón Enrique J, Pollán Marina, Medrano Francisco J
Service de Santé Étudiants, Campus Arras, University of Artois, 62000 Arras, France.
Escuela Internacional de Doctorado, University of Seville, 41004 Seville, Spain.
J Clin Med. 2023 Aug 24;12(17):5507. doi: 10.3390/jcm12175507.
In 2020, Spain ranked fourth among European countries with the highest excess mortality due to COVID-19 disease. This study evaluates the impact of the COVID-19 pandemic on non-COVID patients in a tertiary hospital during the second pandemic wave in Spain (22 June 2020-6 December 2020). Data from Virgen del Rocío University Hospital in Seville during that timeframe were compared with the data from the same period in the preceding two years (2018-2019). Between-group comparisons were performed using the Chi-squared test, Student's -test, or Mann-Whitney U tests, as appropriate. A total of 63,137 non-COVID patients were included in this study. During the second pandemic wave, a 19% decrease was observed in the annual number of non-COVID admissions overall (18,260 vs. 22,439, < 0.001), but a 10% increase in the proportion of emergency admissions (60.6% vs. 54.93%, < 0.001), a higher severity level of patients (1.79 vs. 1.72, < 0.001), a longer in-hospital stay (7.02 vs. 6.74 days, < 0.001), a 26% increase in non-COVID mortality (4.9% vs. 3.9%, < 0.001), and a 50% increase in global mortality (5.9 vs. 3.9, < 0.001) were also observed. In terms of both medical and surgical diagnoses, a significant reduction in the number of admissions and an increase in in-hospital mortality were observed. These results demonstrate the significant impact of the pandemic on hospital care, similar to what was previously observed during the initial wave in the same hospital. Our findings emphasize the need to include non-COVID patients when assessing the broad impact of the pandemic on healthcare, beyond its direct effects on COVID-19 patients.
2020年，在因新冠疫情导致超额死亡率最高的欧洲国家中，西班牙排名第四。本研究评估了西班牙第二波疫情期间（2020年6月22日至2020年12月6日）新冠疫情对一家三级医院非新冠患者的影响。将塞维利亚维根德洛西奥大学医院在该时间段的数据与前两年（2018 - 2019年）同期的数据进行了比较。组间比较根据情况使用卡方检验、学生t检验或曼-惠特尼U检验。本研究共纳入63137名非新冠患者。在第二波疫情期间，总体非新冠住院患者年度数量下降了19%（18260例对22439例，<0.001），但急诊入院比例增加了10%（60.6%对54.93%，<0.001），患者病情严重程度更高（1.79对1.72，<0.001），住院时间更长（7.02天对6.74天，<0.001），非新冠死亡率增加了26%（4.9%对3.9%，<0.001），总体死亡率增加了50%（5.9对3.9，<0.001）。在医学和外科诊断方面，入院人数均显著减少，住院死亡率增加。这些结果表明疫情对医院护理产生了重大影响，与该医院第一波疫情期间之前观察到的情况类似。我们的研究结果强调，在评估疫情对医疗保健的广泛影响时，除了其对新冠患者的直接影响外，还需要纳入非新冠患者。
