Orsi Michele, Janneh Foday Musa, Sesay Amadu, Bah Abdul Karim, Tiru Nitsuh Addis
Unit of Obstetrics, Department of Woman Newborn and Child, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico, Via della Commenda, 12, 20122 Milan, Italy.
Princess Christian Maternity Hospital, University of Sierra Leone Teaching Hospital Complex, Fourah Bay Road, Freetown 00232, Sierra Leone.
J Clin Med. 2023 Aug 30;12(17):5642. doi: 10.3390/jcm12175642.
Guidelines recommend the prompt surgical removal of any ectopic pregnancy (EP) in the presence of a vital embryo. This treatment impacts future fertility, particularly in low-resource settings where access to assisted reproductive techniques is limited. In addition, growing evidence is reporting live births after conservative management of initially undiagnosed abdominal pregnancies. Therefore, the discussion on the acceptability of expectant management in selected cases has been recently raised.
We present and discuss the case of a woman with vital first trimester EP who refused surgical treatment at Princess Christian Maternity Hospital, Freetown, Sierra Leone. She was initially diagnosed with a 12 week pregnancy located in the left adnexal region without hemoperitoneum. She refused both surgical treatment and hospital admission and did not come back to the hospital for antenatal care until 26 weeks of gestational age. Therefore, she was admitted and finally delivered, at 34 weeks of gestation, a 1.9 kg healthy baby which was alive. To disentangle the potential conflict between the ethical principles of medical treatment's beneficence and the patient's autonomy, we provide an update on counselling for a patient with early vital EP in a resource-limited setting and discuss the knowledge gap in this area.
Limited access to fertility treatment in low- and middle-income countries may justify the discussion of expectant management as an option in selected cases of uncomplicated vital EP.
指南建议,一旦发现存活胚胎,应立即手术切除任何异位妊娠(EP)。这种治疗方法会影响未来的生育能力,在辅助生殖技术获取受限的资源匮乏地区尤其如此。此外,越来越多的证据表明,对最初未诊断出的腹腔妊娠进行保守治疗后有活产情况发生。因此,最近引发了关于在特定病例中期待疗法可接受性的讨论。
我们呈现并讨论了一名妊娠早期异位妊娠且胚胎存活的女性病例,该女性拒绝了在塞拉利昂弗里敦的克里斯蒂安公主妇产医院进行手术治疗。她最初被诊断为妊娠12周,孕囊位于左侧附件区,无腹腔内出血。她既拒绝手术治疗也拒绝住院,直到孕26周才返回医院进行产前检查。因此,她入院后最终在孕34周分娩出一个体重1.9千克的健康活婴。为了厘清医疗行善伦理原则与患者自主权之间的潜在冲突,我们提供了在资源有限环境下对早期胚胎存活的异位妊娠患者进行咨询的最新情况,并讨论了该领域的知识空白。
在低收入和中等收入国家,获取生育治疗的机会有限,这可能为在某些单纯性胚胎存活的异位妊娠病例中讨论期待疗法作为一种选择提供了依据。