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胸椎后纵韧带骨化症的后路减压与固定:一项10年随访研究。

Posterior Decompression and Fixation for Thoracic Spine Ossification: A 10-Year Follow-Up Study.

作者信息

Maruyama Juntaro, Furuya Takeo, Maki Satoshi, Inoue Takaki, Yunde Atsushi, Miura Masataka, Shiratani Yuki, Nagashima Yuki, Shiga Yasuhiro, Inage Kazuhide, Eguchi Yawara, Orita Sumihisa, Takahashi Hiroshi, Koda Masao, Yamazaki Masashi, Ohtori Seiji

机构信息

Department of Orthopedics Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8677, Japan.

Center for Frontier Medical Engineering, Chiba University, Chiba 263-8522, Japan.

出版信息

J Clin Med. 2023 Sep 1;12(17):5701. doi: 10.3390/jcm12175701.

Abstract

Ossification of the posterior longitudinal ligament of the thoracic spine (T-OPLL) causes symptoms including leg and back pain, and motor and sensory deficits. This study retrospectively reviewed 32 patients who initially underwent posterior decompression with instrumented fusion (PDF) for T-OPLL between 2001 and 2012, with 20 qualifying for the final analysis after applying exclusion criteria. Exclusions included unknown preoperative neurological findings, follow-up less than 10 years, or prior spinal surgeries at other levels. Outcomes were assessed using the Japanese Orthopedic Association (JOA) score, recovery rate, and kyphotic angle. The average preoperative JOA score of 3.6 improved to 7.4 at 1 year post-surgery and remained at 7.4 at 10 years, with a recovery rate of 52%. The kyphotic angle at T4-12 increased from 26 degrees preoperatively to 29 degrees postoperatively and to 37 degrees at 10 years. At the fused levels, the angle remained at 26 degrees immediately post-operation and increased to 32 degrees at 10 years. Forty percent of patients required additional surgery, primarily for conditions related to cervical OPLL, such as myelopathy, or lumbar OPLL, such as radiculopathy, or cauda equina syndrome. In conclusion, PDF effectively reduces T-OPLL symptoms over the long term, but the high rate of additional surgeries calls for careful patient follow-up.

摘要

胸椎后纵韧带骨化症(T-OPLL)会引发腿部和背部疼痛、运动及感觉功能障碍等症状。本研究回顾性分析了2001年至2012年间最初接受后路减压内固定融合术(PDF)治疗T-OPLL的32例患者,经应用排除标准后,最终有20例符合分析要求。排除标准包括术前神经功能情况不明、随访时间不足10年或曾在其他节段接受过脊柱手术。采用日本骨科学会(JOA)评分、恢复率和后凸角对治疗结果进行评估。术前JOA平均评分为3.6分,术后1年提高至7.4分,术后10年仍维持在7.4分,恢复率为52%。T4-12节段的后凸角术前为26°,术后增至29°,术后10年达到37°。在融合节段,术后即刻角度为26°,术后10年增至32°。40%的患者需要再次手术,主要是针对与颈椎OPLL相关的疾病,如脊髓病,或腰椎OPLL相关疾病,如神经根病或马尾综合征。总之,PDF能长期有效缓解T-OPLL症状,但再次手术率较高,因此需要对患者进行密切随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5156/10488937/6ba42af4cb24/jcm-12-05701-g001.jpg

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