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3299 例黑人患者的胸椎后纵韧带骨化的患病率和特征:前瞻性注册数据库的横断面研究。

Prevalence and characteristics of thoracic ossification of the posterior longitudinal ligament in 3299 Black patients: a cross-sectional study of a prospectively registered database.

机构信息

Department of Orthopaedic Surgery & Rehabilitation Medicine, SUNY Downstate Medical Center, Brooklyn, New York, USA

Department of Orthopaedic Surgery, NYC Health and Hospitals-Kings County, Brooklyn, New York, USA.

出版信息

BMJ Open. 2022 Aug 26;12(8):e059238. doi: 10.1136/bmjopen-2021-059238.

DOI:10.1136/bmjopen-2021-059238
PMID:36028263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9422829/
Abstract

OBJECTIVES

To the best of our knowledge, the prevalence of thoracic ossification of the posterior longitudinal ligament (T-OPLL) in the Black population has never been studied and is still unknown. The purpose of this study was to examine the prevalence and characteristics of T-OPLL in the Black patients.

METHODS

This is a cross-sectional study. All patients who underwent chest CT for the trauma screening and whose race was classified as 'Black' on the questionnaire were recruited in the study from March 2019 to March 2020. Demographic data, including age, sex, body mass index (BMI) and presence of diabetes mellitus (DM), were recorded. T-OPLL was defined as ectopic OPLL of more than 2 mm thickness in the axial plane image of the CT scan. The prevalence and characteristics of T-OPLL, and the association of T-OPLL with BMI and DM were evaluated.

RESULTS

A total of 3299 Black patients (1507 women and 1792 men) were included for the analysis. The prevalence of T-OPLL was 1.5% (50 patients), with 2.4% for females and 0.8% for males. The highest prevalence was observed in patients at the age of 70 years (3.8%). Thickness of T-OPLL was between 2 and 3 mm in 46% (23/50) of the patients, and the largest thickness was 6.1 mm. T-OPLL was significantly associated with female sex and the presence of DM.

CONCLUSIONS

The prevalence of T-OPLL was 1.5% in the 3299 Black patients who underwent chest CT for the trauma screening, with 2.4% for females and 0.8% for males.

摘要

目的

据我们所知,黑人中胸段后纵韧带骨化(T-OPLL)的患病率从未被研究过,目前尚不清楚。本研究的目的是研究黑人患者中 T-OPLL 的患病率和特征。

方法

这是一项横断面研究。从 2019 年 3 月至 2020 年 3 月,所有因创伤筛查而行胸部 CT 的患者,且问卷种族分类为“黑人”的患者均被纳入研究。记录人口统计学数据,包括年龄、性别、体重指数(BMI)和糖尿病(DM)的存在。T-OPLL 定义为 CT 扫描轴位图像中外层 OPLL 的厚度超过 2mm。评估 T-OPLL 的患病率和特征,以及 T-OPLL 与 BMI 和 DM 的关系。

结果

共纳入 3299 名黑人患者(1507 名女性和 1792 名男性)进行分析。T-OPLL 的患病率为 1.5%(50 例),女性为 2.4%,男性为 0.8%。70 岁患者的患病率最高(3.8%)。T-OPLL 的厚度在 46%(23/50)的患者中在 2-3mm 之间,最大厚度为 6.1mm。T-OPLL 与女性性别和 DM 的存在显著相关。

结论

在 3299 名因创伤筛查而行胸部 CT 的黑人患者中,T-OPLL 的患病率为 1.5%,女性为 2.4%,男性为 0.8%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f9/9422829/7893c5706ecf/bmjopen-2021-059238f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f9/9422829/c050010825e8/bmjopen-2021-059238f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f9/9422829/e493a1427c80/bmjopen-2021-059238f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f9/9422829/7893c5706ecf/bmjopen-2021-059238f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f9/9422829/c050010825e8/bmjopen-2021-059238f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f9/9422829/e493a1427c80/bmjopen-2021-059238f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90f9/9422829/7893c5706ecf/bmjopen-2021-059238f03.jpg

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