Tamurejo-Alonso Purificación, González-Martín María Luisa, Pacha-Olivenza Miguel Ángel
Department of Biomedical Science, Faculty of Medicine and Health Sciences, University of Extremadura, 06006 Badajoz, Spain.
University Institute of Extremadura Sanity Research (INUBE), 06006 Badajoz, Spain.
Materials (Basel). 2023 Aug 31;16(17):5985. doi: 10.3390/ma16175985.
The improvement of biodegradable metals is currently an active and promising research area for their capabilities in implant manufacturing. However, controlling their degradation rate once their surface is in contact with the physiological media is a challenge. Surface treatments are in the way of addressing the improvement of this control. Zinc is a biocompatible metal present in the human body as well as a metal widely used in coatings to prevent corrosion, due to its well-known metal protective action. These two outstanding characteristics make zinc coating worthy of consideration to improve the degradation behaviour of implants. Electrodeposition is one of the most practical and common technologies to create protective zinc coatings on metals. This article aims to review the effect of the different parameters involved in the electrochemical process on the topography and corrosion characteristics of the zinc coating. However, certainly, it also provides an actual and comprehensive description of the state-of-the-art of the use of electrodeposited zinc for biomedical applications, focusing on their capacity to protect against bacterial colonization and to allow cell adhesion and proliferation.
目前，可生物降解金属因其在植入物制造方面的能力，是一个活跃且有前景的研究领域。然而，一旦其表面与生理介质接触，控制其降解速率是一项挑战。表面处理是解决这一控制问题的方法。锌是一种存在于人体中的生物相容性金属，也是一种广泛用于涂层以防止腐蚀的金属，因其具有众所周知的金属保护作用。这两个突出特性使得锌涂层在改善植入物降解行为方面值得考虑。电沉积是在金属上制备保护性锌涂层最实用、最常见的技术之一。本文旨在综述电化学过程中涉及的不同参数对锌涂层形貌和腐蚀特性的影响。当然，它也实际且全面地描述了电沉积锌在生物医学应用方面的最新进展，重点关注其防止细菌定植以及促进细胞黏附与增殖的能力。
