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Why are neuromelanin-containing dopaminergic neurons lost in idiopathic Parkinson's disease?

作者信息

Huenchuguala Sandro, Segura-Aguilar Juan

机构信息

Escuela de Tecnología Médica, Facultad de Salud, Universidad Santo Tomás, Los Carreras 753, Osorno, Chile.

Molecular and Clinical Pharmacology, ICBM, Faculty of Medicine, University of Chile, Santiago, Chile.

出版信息

Cell Mol Life Sci. 2023 Sep 9;80(10):281. doi: 10.1007/s00018-023-04880-y.

Abstract
摘要

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本文引用的文献

1
Neuromelanin magnetic resonance imaging of substantia nigra and locus coeruleus in Parkinson's disease with freezing of gait.
Front Aging Neurosci. 2023 Feb 2;15:1060935. doi: 10.3389/fnagi.2023.1060935. eCollection 2023.
2
The link between neuroinflammation and the neurovascular unit in synucleinopathies.
Sci Adv. 2023 Feb 15;9(7):eabq1141. doi: 10.1126/sciadv.abq1141.
3
Neuroprotection against Aminochrome Neurotoxicity: Glutathione Transferase M2-2 and DT-Diaphorase.
Antioxidants (Basel). 2022 Jan 31;11(2):296. doi: 10.3390/antiox11020296.
4
Astrocytes protect dopaminergic neurons against aminochrome neurotoxicity.
Neural Regen Res. 2022 Sep;17(9):1861-1866. doi: 10.4103/1673-5374.335690.
5
Extracellular Vesicles as Novel Diagnostic and Prognostic Biomarkers for Parkinson's Disease.
Aging Dis. 2021 Sep 1;12(6):1494-1515. doi: 10.14336/AD.2021.0527. eCollection 2021 Sep.
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Neuromelanin Imaging and Dopaminergic Loss in Parkinson's Disease.
Front Aging Neurosci. 2016 Aug 22;8:196. doi: 10.3389/fnagi.2016.00196. eCollection 2016.

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