Department of Respiratory and Critical Care Medicine, National Center for Respiratory Medicine, State Key Lab of Respiratory Disease, The first affiliated hospital of Guangzhou Medical University, 151 Yanjiang Road, Guangzhou, 510120, China.
Department of Allergy and Clinical Immunology, National Center for Respiratory Medicine, State Key Lab of Respiratory Disease, The first affiliated hospital of Guangzhou Medical University, Guangzhou, China.
BMC Pulm Med. 2023 Sep 9;23(1):336. doi: 10.1186/s12890-023-02568-4.
Endobronchial ultrasonography-guided transbronchial needle aspiration biopsy (EBUS-TBNA) has been used for more than 10 years in China. Its clinical application and diagnostic value in different diseases with large sample was lack of report.
A retrospective analysis was performed about the application and diagnostic value of EBUS-TBNA in different disease of patients in Respiratory Intervention Center of Guangzhou Institute of Respiratory Health from January 2012 to July 2020.
A total 5758 patients were included with 182 patients excluded for lack of information. Finally, data of 5576 patients (3798 males and 1778 females) were analyzed. For anesthetize, most patients were undergoing general anesthesia of intravenous with spontaneous breathing (69.4%), followed by general anesthesia of intravenous and inhalation with tracheal intubation and mechanical ventilation (17.9%) and conscious sedation and analgesia (12.8%). Lymph nodes were the main sites of biopsy obtained (76.4%). Tumors accounted for the highest proportion of disease (66.4%), followed by infection diseases (9.9%), sarcoidosis (3.9%), lymphoma (1.1%), and others (18.7%). The sensitivity of EBUS-TBNA for diagnosis of tumor was 89.7%, and 40.8% for infection diseases. There were significant differences in the puncture site and proportions of diseases between male and females (both p < 0.05). Higher diagnostic value was found in male patients (p < 0.05).
EBUS-TBNA has good diagnostic value for different mediastinal and central pulmonary space-occupying lesions diseases, with highest sensitivity for tumors. Higher diagnostic value was found in male patients.
支气管内超声引导经支气管针吸活检（EBUS-TBNA）在中国已经使用了 10 多年。缺乏关于其在不同疾病中应用及诊断价值的大样本报告。
回顾性分析了 2012 年 1 月至 2020 年 7 月广州呼吸健康研究院呼吸介入中心 5758 例患者应用 EBUS-TBNA 的情况及诊断价值。
排除信息不全的 182 例患者后，共纳入 5576 例患者（男 3798 例，女 1778 例）。麻醉方式以静脉全身麻醉下自主呼吸为主（69.4%），其次为静脉全身麻醉下气管插管机械通气（17.9%）和镇静镇痛（12.8%）。活检部位主要为淋巴结（76.4%）。病变性质以肿瘤为主（66.4%），其次为感染性疾病（9.9%）、结节病（3.9%）、淋巴瘤（1.1%）和其他（18.7%）。EBUS-TBNA 诊断肿瘤的敏感度为 89.7%，诊断感染性疾病的敏感度为 40.8%。男女患者穿刺部位和疾病构成比差异均有统计学意义（均 P<0.05），男性患者诊断效能更高（均 P<0.05）。
EBUS-TBNA 对不同的纵隔和中央肺部占位性病变疾病具有良好的诊断价值，对肿瘤的敏感度最高。男性患者诊断效能更高。
Zotero 插件
