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接受非自愿治疗的极度严重神经性厌食症患者的纵向研究。

Longitudinal investigation of patients receiving involuntary treatment for extremely severe anorexia nervosa.

机构信息

Clinique des Maladies Mentales et de l'Encéphale, Hôpital Sainte-Anne, GHU Paris Psychiatrie et Neurosciences, Paris, France.

Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Paris, France.

出版信息

Eur Eat Disord Rev. 2024 Mar;32(2):179-187. doi: 10.1002/erv.3033. Epub 2023 Sep 10.

Abstract

INTRODUCTION

Involuntary treatment may be a life-saving option for extremely severe anorexia nervosa (AN) in the context of life-threatening conditions and refusal of care. The long-term outcomes of patients undergoing involuntary treatment for AN are poorly understood. This study aims to explore quality of life, long-term outcomes and attitudes towards involuntary treatment in patients involuntarily treated for extremely severe AN.

METHODS

23 patients involuntarily admitted for extremely severe AN (I-AN), and 25 voluntarily admitted patients (V-AN) were compared for body mass index (BMI), residual symptoms, quality of life, and attitudes towards treatment almost four years after discharge. In I-AN, clinical variables were also compared between admission and follow-up.

RESULTS

At follow-up, weight restoration was higher in V-AN (p = 0.01), while differences in quality of life, BMI, and mortality rates were not significant between I-AN and V-AN (p > 0.05). In I-AN, BMI increased and weight-controlling strategies decreased at follow-up (p < 0.05). Despite negative experiences of involuntary treatment, the perception of the necessity of treatment increased from admission to follow-up (p < 0.01) and became comparable to V-AN (p > 0.05).

DISCUSSION

Involuntary treatment for AN does not appear to be a barrier to weight gain and clinical improvement, nor to long-term attitudes towards treatment.

摘要

简介

在危及生命的情况下和拒绝治疗时,非自愿治疗可能是治疗极度严重厌食症(AN)的一种挽救生命的选择。接受非自愿治疗的 AN 患者的长期结果知之甚少。本研究旨在探讨因极度严重 AN 而接受非自愿治疗的患者的生活质量、长期结果和对非自愿治疗的态度。

方法

比较了 23 名因极度严重 AN(I-AN)而被非自愿住院的患者和 25 名自愿住院的患者(V-AN)的体重指数(BMI)、残留症状、生活质量和治疗态度,这些患者在出院后近四年时接受了评估。在 I-AN 中,还比较了入院和随访时的临床变量。

结果

在随访时,V-AN 的体重恢复更高(p=0.01),而 I-AN 和 V-AN 之间的生活质量、BMI 和死亡率差异不显著(p>0.05)。在 I-AN 中,BMI 在随访时增加,而控制体重的策略减少(p<0.05)。尽管对非自愿治疗有负面体验,但对治疗必要性的认知从入院到随访时增加(p<0.01),并与 V-AN 相当(p>0.05)。

讨论

非自愿治疗 AN 似乎不会成为体重增加和临床改善的障碍,也不会成为长期治疗态度的障碍。

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