半不稳定的P，N-配体辅助的芳基和苯乙烯基碘化物与苯乙烯的金催化Heck反应。
Hemilabile P,N-Ligand-Assisted Gold-Catalyzed Heck Reaction of Aryl and Styryl Iodides with Styrenes.
作者信息
Wei Cunbo, Zhang Lizhu, Xia Zhonghua
机构信息
School of Materials Science & Engineering, Beijing Institute of Technology, Beijing 100081, China.
出版信息
Org Lett. 2023 Sep 22;25(37):6808-6812. doi: 10.1021/acs.orglett.3c02244. Epub 2023 Sep 10.
A gold-catalyzed Heck reaction of aryl and styryl iodides with styrenes was developed. The hemilabile P,N-ligand-assisted gold-catalyzed C(sp)-C(sp) cross-coupling can synthesize stilbenes and bistyryl complexes, with good functional-group tolerance and mild conditions. The elementary organometallic steps of migratory insertion and β-hydride elimination might be involved in this ligand-enabled Au(I)/Au(III)-catalyzed Heck reaction with styrenes.
开发了一种芳基和苯乙烯基碘与苯乙烯的金催化Heck反应。半不稳定的P，N配体辅助的金催化C(sp)-C(sp)交叉偶联可以合成二苯乙烯和双苯乙烯基配合物，具有良好的官能团耐受性和温和的条件。迁移插入和β-氢消除的基本有机金属步骤可能参与了这种由配体介导的Au(I)/Au(III)催化的与苯乙烯的Heck反应。
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