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Improved understanding of NSCLC immunotherapy response mechanisms from single-cell analysis.

作者信息

Bienkowska Kamila Justyna, Hanley Christopher Jon

机构信息

School of Cancer Sciences, University of Southampton, Southampton, UK.

出版信息

Transl Lung Cancer Res. 2023 Aug 30;12(8):1807-1811. doi: 10.21037/tlcr-23-428. Epub 2023 Aug 8.

DOI:10.21037/tlcr-23-428
PMID:37691874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10483077/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f331/10483077/817672ab7291/tlcr-12-08-1807-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f331/10483077/817672ab7291/tlcr-12-08-1807-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f331/10483077/817672ab7291/tlcr-12-08-1807-f1.jpg

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本文引用的文献

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Genome Med. 2023 Mar 3;15(1):14. doi: 10.1186/s13073-023-01164-9.
2
Tumour-infiltrating B cells: immunological mechanisms, clinical impact and therapeutic opportunities.肿瘤浸润 B 细胞：免疫机制、临床影响和治疗机会。
Nat Rev Cancer. 2022 Jul;22(7):414-430. doi: 10.1038/s41568-022-00466-1. Epub 2022 Apr 7.
3
Tertiary lymphoid structures in cancer.
癌症中的三级淋巴结构。
Science. 2022 Jan 7;375(6576):eabf9419. doi: 10.1126/science.abf9419.
4
Improved prediction of immune checkpoint blockade efficacy across multiple cancer types.改善多种癌症类型的免疫检查点阻断疗效预测。
Nat Biotechnol. 2022 Apr;40(4):499-506. doi: 10.1038/s41587-021-01070-8. Epub 2021 Nov 1.
5
A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells.泛癌种肿瘤浸润髓系细胞的单细胞转录组图谱。
Cell. 2021 Feb 4;184(3):792-809.e23. doi: 10.1016/j.cell.2021.01.010.
6
The Significance of Secreted Phosphoprotein 1 in Multiple Human Cancers.分泌型磷蛋白1在多种人类癌症中的意义
Front Mol Biosci. 2020 Nov 24;7:565383. doi: 10.3389/fmolb.2020.565383. eCollection 2020.
7
Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer.单细胞分析揭示与癌症免疫治疗耐药相关的成纤维细胞簇。
Cancer Discov. 2020 Sep;10(9):1330-1351. doi: 10.1158/2159-8290.CD-19-1384. Epub 2020 May 20.
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Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15 Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy.单细胞 RNA 测序揭示了间质向 LRRC15 肌成纤维细胞的演化是决定癌症免疫治疗患者反应的决定因素。
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