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感染伯纳特柯克斯体的牛与接种疫苗后牛的IgG1和IgG2反应差异。

Differences in IgG1 and IgG2 responses of cattle infected with Coxiella burnetii and following vaccination.

作者信息

Schmeer N, Krauss H, Lohrbach W, Wiegand D

出版信息

Comp Immunol Microbiol Infect Dis. 1986;9(1):95-8. doi: 10.1016/0147-9571(86)90080-9.

DOI:10.1016/0147-9571(86)90080-9
PMID:3769444
Abstract

Vaccination of 115 cattle with a formalin-inactivated Coxiella burnetii (Phase II) vaccine selectively induced a highly significant IgG2 response detectable by enzyme-linked immunosorbent assay. High IgG2 and negative or cut off IgG1 levels could be detected in uninfected cattle, whereas significant IgG1 but lower IgG2 levels were associated with C. burnetii infections.

摘要

用福尔马林灭活的贝氏柯克斯体（II期）疫苗对115头牛进行接种，通过酶联免疫吸附测定法可选择性诱导出高度显著的IgG2反应。在未感染的牛中可检测到高IgG2水平以及阴性或临界IgG1水平，而显著的IgG1水平但较低的IgG2水平与贝氏柯克斯体感染有关。

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Differences in IgG1 and IgG2 responses of cattle infected with Coxiella burnetii and following vaccination.感染伯纳特柯克斯体的牛与接种疫苗后牛的IgG1和IgG2反应差异。
Comp Immunol Microbiol Infect Dis. 1986;9(1):95-8. doi: 10.1016/0147-9571(86)90080-9.
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引用本文的文献

1
Enzyme-linked immunosorbent fluorescence assay and high-pressure liquid chromatography for analysis of humoral immune responses to Coxiella burnetti proteins.酶联免疫吸附荧光分析法和高压液相色谱法用于分析针对伯纳特柯克斯体蛋白的体液免疫反应。
J Clin Microbiol. 1988 Dec;26(12):2520-5. doi: 10.1128/jcm.26.12.2520-2525.1988.
2
Clinical aspects and prevention of Q fever in animals.
Eur J Epidemiol. 1989 Dec;5(4):420-4. doi: 10.1007/BF00140132.